Results 91 to 100 of about 4,023,817 (302)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Machine learning-enabled chemical space exploration of all-inorganic perovskites for photovoltaics

npj Computational Materials
The vast compositional and configurational spaces of multi-element metal halide perovskites (MHPs) result in significant challenges when designing MHPs with promising stability and optoelectronic properties.
Jin-Soo Kim, Juhwan Noh, Jino Im
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

METHOD TIME DRIVEN ACTIVITY BASED COSTING – LITERATURE REVIEW [PDF]

This article presents a literature review of the method Time Driven Activity Based Costing, like an instrument to better assignment of costs to activities and their comparison with antecedent method Activity Based Costing.
Oleg DEJNEGA
core  

Models, Modeling, and Model-Driven Development

, 2020
Models can be refined and finally be transformed into a technical implementation, i.e., a software system.
Brown, AW
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

ClimActor 2.0: A spatialized database of subnational climate pledges and emissions data

Scientific Data
ClimActor 2.0 is an open, spatialized database that compiles climate targets, action plans, and self-reported emission inventories from subnational governments, including cities, municipalities, states and regions, worldwide.
Diego Manya, Katherine Burley Farr, Elizabeth Brown, Andrew Martin, Angel Hsu   +4 more
doaj   +1 more source

Implementation and dissemination of a transition of care program for rural veterans: a controlled before and after study

Implementation Science, 2017
Background Adapting promising health care interventions to local settings is a critical component in the dissemination and implementation process. The Veterans Health Administration (VHA) rural transitions nurse program (TNP) is a nurse-led, Veteran ...
Chelsea Leonard, Emily Lawrence, Marina McCreight, Brandi Lippmann, Lynette Kelley, Ashlea Mayberry, Amy Ladebue, Heather Gilmartin, Murray J. Côté, Jacqueline Jones, Borsika A. Rabin, P. Michael Ho, Robert Burke   +12 more
doaj   +1 more source