Results 61 to 70 of about 177,671 (299)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Analysis of the Variability of Axial Bearing Capacity Piles in Cohesionless Soil in the Development of Meyerhof Formula

open access: yesJurnal Teknik Sipil
Abstrak   Rumus daya dukung pondasi tiang dari Meyerhof (1976) banyak digunakan di Indonesia. Sangat penting untuk mengkuantifikasi variabilitas dalam perancangan.
Sugeng Krisnanto   +5 more
doaj   +1 more source

Axial capacity ageing trends of large diameter tubular piles driven in sand

open access: yesSoils and Foundations, 2023
The paper examines dynamic pile test data from 25 high-quality offshore cases, where end-of-initial driving (EoID) and beginning-of-restrike (BoR) instrumented dynamic monitoring was undertaken on tubular piles driven in sands at well-characterised sites
D. Cathie   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The Impact of EC 7 in Axial Load Capacity Estimation of Pile Foundations [PDF]

open access: yes, 2013
The pile foundation is generally used in Albania. Until today their design is based onwhat it is called The Albanian Practice of Design. In these days, the implementation of theEurocode in the design, is considered very fundamental.
Alketa Ndoj   +3 more
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Behaviour of jacked and driven piles in sandy soil [PDF]

open access: yes, 2006
As an alternative to conventional dynamic pile installation methods, pile jacking is an environmentally friendly technique that could become more widely accepted.
Chan, ST   +4 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Macroscopic control parameter for avalanche models for bursty transport [PDF]

open access: yes, 2009
Similarity analysis is used to identify the control parameter RA for the subset of avalanching systems that can exhibit self-organized criticality (SOC). This parameter expresses the ratio of driving to dissipation. The transition to SOC, when the number
Bohr T.   +10 more
core   +3 more sources

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