Results 131 to 140 of about 2,232,082 (389)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Integrating Industrial Laser Scanners for Small Vessel Operations [PDF]

, 2015
The NOAA Navigation Response Teams (NRTs) perform hydrographic surveys to support nautical charting updates for 175 ports of the United States Marine Transportation System.These include the identification of bathymetric and anthropogenic features that ...
Maddock, David, Murray, Bryan, Oroshnik, David, Pe\u27eri, Shachak, Pradith, Vitad, Riley, Jack   +5 more
core   +1 more source

Hospital Readmission After Traumatic Brain Injury Hospitalization in Community‐Dwelling Older Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the risk of hospital readmission after an index hospitalization for TBI in older adults. Methods Using data from the Atherosclerosis Risk in Communities (ARIC) study, we used propensity score matching of individuals with an index TBI‐related hospitalization to individuals with (1) non‐TBI hospitalizations (primary analysis)
Rachel Thomas, Connor A. Law, Joan A. Casey, Thomas Mosley, Rebecca F. Gottesman, Ramon Diaz‐Arrastia, Holly Elser, Andrea L. C. Schneider   +7 more
wiley   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

DRIVEN POLYSTRONG REINFORCED CONCRETE PILES AND NEW DESIGN OF PILE CAPS

Наука и техника, 2015
The paper presents constructional and technological features for manufacturing driven piles with variable strength of pile shaft. Economical efficiency of their production has been shown in the paper.
I. I. Bekbasarov, G. I. Isakov
doaj  

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

The load-transfer method as a tool for determining the load-displacement curve of piles

Acta Polytechnica
The paper presents two applications (software packages) in which the load-transfer method is used for axially loaded Kelly drilled bored piles and displacement ductile iron piles.
Juraj Chalmovský, Václav Račanský, Pavel Koudela, Karel Zdražil   +3 more
doaj   +1 more source

Cptu-Based Axial Capacity of Driven Piles in Saline Interlayered Silty Deposits: The Case of Tehran-Isfahan High-Speed Railway Project

, 2023
M. R. Khodayari, S. M. Mousavizadeh, Mohammad Mehdi Ahmadi   +2 more
openalex   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Study on the side friction resistance capacity of prefabricated pipe piles in coral reef strata

Frontiers in Earth Science
Coral reefs are widely distributed along the “Maritime Silk Road”, and their unique mechanical properties pose numerous challenges for marine engineering construction.
Hong Zhang, Ran Gao, Ran Gao, Huiwu Luo, Peishuai Chen, Haifeng Liu   +5 more
doaj   +1 more source