Results 111 to 120 of about 2,232,082 (389)

Time distribution and loss of scaling in granular flow

open access: yes, 1999
Two cellular automata models with directed mass flow and internal time scales are studied by numerical simulations. Relaxation rules are a combination of probabilistic critical height (probability of toppling $p$) and deterministic critical slope ...
Tadic, Bosiljka
core   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Large Scale Tests on Buoyancy-Driven Vertical Piling Breakwater with Buoyancy-Driven Piles

open access: yesPROCEEDINGS OF COASTAL ENGINEERING, JSCE, 2008
This report describes the results of the large scale model tests on the buoyancy-driven vertical piling breakwater by using the buoyancy-driven piles. This breakwater consists of rows of steel pip. piles and each pile consists of upper and lower steel pipes.
Taro ARIKAWA   +6 more
openaire   +2 more sources

Statistics of model factors in reliability-based design of axially loaded driven piles in sand

open access: yesCanadian geotechnical journal (Print), 2018
This paper compiles 162 reliable field load tests for axially loaded driven piles in sand from previous studies. The L1–L2 method is adopted to interpret the measured resistance from the load–settlement data.
Chong Tang, K. Phoon
semanticscholar   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Eliciting Expertise

open access: yes, 2005
Since the last edition of this book there have been rapid developments in the use and exploitation of formally elicited knowledge. Previously, (Shadbolt and Burton, 1995) the emphasis was on eliciting knowledge for the purpose of building expert or ...
Shadbolt, N R
core   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Construction techniques for cross-sea bridges in coral reef and island environments

open access: yesFrontiers in Earth Science
Coral islands and reefs serve as the sole land-based foundations in the open ocean, and their unique engineering characteristics pose significant challenges for cross-sea bridge construction.
Yu Zhong   +5 more
doaj   +1 more source

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