Results 51 to 60 of about 725,128 (304)

An adaptive agent digraph simulation for road traffic safety statue in bridge–tunnel groups

Advances in Mechanical Engineering, 2017
The safety state of road network in the bridge–tunnel groups is an important factor in evaluating road traffic safety. This article describes a case study simulating brittleness behavior of road traffic safety statue in the bridge–tunnel groups.
Jibiao Zhou, Sheng Dong, Bin Yan, Minjie Zhang, Renfa Yang   +4 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Use and access possibilities in the field of training future drivers using a vehicle simulator

Acta Polytechnica CTU Proceedings
Novice drivers between the ages of 18 and 24 have a higher risk of accidents, which results from long-term published statistical data. The goal of training at driving schools should be the comprehensive preparation of future drivers for all traffic ...
Libor Topol
doaj   +1 more source

Ensihoitajien kokemuksia hälytysajosta Pohjois-Savon sairaanhoitopiirin alueella [PDF]

, 2018
Ambulanssin ajaminen ja hälytysajo ovat olennainen osa ensihoitajan ammattia. Suomessa ambulanssi on vuosittain osallisena useissa liikenneonnettomuuksissa. Turvallinen hälytysajo on merkittävä osa ensihoidon työturvallisuutta. Hälytysajon turvallisuutta
Haatainen, Katri, Suomalainen, Jemiina, Väisänen, Nina   +2 more
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Runway incursions: Airport movement area driver training demographics suggests revisions to airport driver training methods [PDF]

, 2009
This paper examines the problem of runway incursions at the (OEP-35) U.S. towered airports. According to the FAA Runway Safety Report (2004), vehicle deviations accounted for 20% (291 events) of all runway incursions during the period of 2000 through ...
Cokley, John D., Rankin, William
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Evaluation of the Effectiveness of Driver Training in the Use of Advanced Driver Assistance Systems

Applied Sciences
This paper evaluates the effectiveness of driver training programmes aimed at the proper use of Advanced Driver Assistance Systems (ADASs). Participants (N = 49) were divided into the following three groups based on the type of training received ...
Małgorzata Pełka, Adam Rosiński
doaj   +1 more source

Promoting transportation safety in adolescence: the drivingly randomized controlled trial

BMC Public Health, 2023
Background The impact of young drivers’ motor vehicle crashes (MVC) is substantial, with young drivers constituting only 14% of the US population, but contributing to 30% of all fatal and nonfatal injuries due to MVCs and 35% ($25 billion) of the all ...
Jessica Hafetz, Catherine C. McDonald, D. Leann Long, Carol A. Ford, Thandwa Mdluli, Andrew Weiss, Jackson Felkins, Nicole Wilson, Bradley MacDonald   +8 more
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source