Results 81 to 90 of about 1,572,522 (294)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Sensor-Detected Differences in Behaviors of Older Drivers with Pre-MCI and Mild Cognitive Impairment vs. Unimpaired Drivers

Sensors
Background: Research to identify changes in driving behavior that occur with the onset of Pre-MCI and MCI is an emerging area with many gaps still to be addressed.
Ruth M. Tappen, David Newman, Mónica Rosselli, Joshua Conniff, Subhosit Ray, Sonia Moshfeghi, Jinwoo Jang, KwangSoo Yang, Borko Furht   +8 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Stroboscopic prethermalization in weakly interacting periodically driven systems

, 2016
Time-periodic driving provides a promising route to engineer non-trivial states in quantum many-body systems. However, while it has been shown that the dynamics of integrable systems can synchronize with the driving into a non-trivial periodic motion ...
Canovi, Elena, Eckstein, Martin, Kollar, Marcus   +2 more
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Research on Driver Driving Behavior Based on Decision Tree

Kongzhi Yu Xinxi Jishu, 2019
Driver driving behavior is one of the important factors affecting energy consumption of vehicle. In order to accurately analyze driving behavior of a driver, correlation analysis of driving behavior parameters through grey correlation analysis was made ...
LI Xi, FENG Ba, XIE Yongbo, WANG Wenming
doaj  

Development of a Safety Index to Identify Differences in Safety Performance by Postal Delivery Motorcyclists Based either in Different Regional Post Offices or within the Same Regional Office

ISPRS International Journal of Geo-Information, 2017
Postal motorcyclists who regularly conduct deliveries are particularly vulnerable to road accidents since they are exposed to traffic throughout their work day. To reduce accident rates, safety officers in each of the local delivery offices alert postmen
Junghee Jo, Hyunsuk Kim
doaj   +1 more source

The effects of alcohol on driver performance in a decision making situation [PDF]

, 1978
The results are reviewed of driving simulator and in-vehicle field test experiments of alcohol effects on driver risk taking. The objective was to investigate changes in risk taking under alcoholic intoxication and relate these changes to effects on ...
Allen, R. W., Hogge, J. R., Schwartz, S. H., Stein, A. C.   +3 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Assessing the relationship between driving skill, driving stress, and driving behavior

Journal of Safety Research
Driving skill, driving stress, and driving behavior have an effect on road traffic safety. Most previous studies have investigated the effect of driving skill or driving stress on driving behavior separately. However, the relationship and effect mechanism between driving skill, driving stress, and driving behavior have been neglected.1207 licensed ...
Yang, Liu, Cheng, Jiahan, Wang, Ziyang, Li, Xiaomeng   +3 more
openaire   +3 more sources