Results 91 to 100 of about 4,808,273 (255)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
A Sensing Architecture Based on Head-Worn Inertial Sensors to Study Drivers’ Visual Patterns
Proceedings, 2019 Most studies on driving behaviors use video-cameras and simulators. It involves human observers to code the video data to be later analyzed, which can be a demanding task.
Josué S. Armenta +2 more
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Stability and change in risky driving from the late teens to the late twenties [PDF]
, 2013 This paper examines patterns of risky driving from the late teens to the late twenties and identifies factors associated with persistence and change in risky driving tendencies.Key findings: Rates of risky driving remained fairly stable between the ...
Suzanne Vassallo +2 more
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Test-retest reliability of simulated driving performance: A pilot study
, 2013 Twenty-seven volunteers completed three simulated driving tests to determine test-retest reliability of performance on a low-cost, fixed-base computerized driving simulator.
Leveritt, Michael +3 more
core
Speech and driving - solution or problem? [PDF]
, 2006 Besides travel related information driver related information plays an increasing role while driving. In order to process this information and be able to drive safely at the same time, an information management is necessary in the vehicle.
Vollrath, Mark
core
The Relationship Between Driving Behavior and Entropy [PDF]
, 2007 OBJECTIVES High variability in the lateral control of a vehicle may result in an increased likelihood of accidents. Boer (2000) proposed a method of quantifying variability in steering wheel position, termed “entropy” (scaled between 0 and 1).
Jeffrey D Dawson +9 more
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Findings from the DUMA program: drink and drug driving among police detainees [PDF]
, 2015 This paper finds that detainees do perceive a risk related to drink and drug driving, in terms of impairment in driving ability and potential detection by police.
Susan Goldsmid +2 more
core