Results 81 to 90 of about 4,808,273 (255)

A comparison of the driving behavior between remunerated and volunteer drivers [PDF]

, 2011
Introduction: Past research suggests that some groups of work-related drivers practice more safe driving behavior than others. However, no research to date has compared the driving behavior of those remunerated for their services and volunteer work ...
Barry Watson, Newnam, Sharon A., Watson, Barry C., Sharon Newnam   +3 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Modelling the Effect of Driving Events on Electrical Vehicle Energy Consumption Using Inertial Sensors in Smartphones

Energies, 2018
Air pollution and climate change are some of the main problems that humankind is currently facing. The electrification of the transport sector will help to reduce these problems, but one of the major barriers for the massive adoption of electric vehicles
David Jiménez, Sara Hernández, Jesús Fraile-Ardanuy, Javier Serrano, Rubén Fernández, Federico Álvarez   +5 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Smart driving aids and their effects on driving performance and driver distraction [PDF]

, 2009
In-vehicle information systems have been shown to increase driver workload and cause distraction; both of which are causal factors for accidents. This simulator study evaluates the impact that two designs for a smart driving aid, and scenario complexity ...
Young, Mark S., Birrell, S.A., Young, Mark, Birrell, Stewart A.   +3 more
core  

Crash risk perception of sleepy driving and its comparisons with drink driving and speeding: which behavior is perceived as the riskiest? [PDF]

, 2016
Objective: Driver sleepiness is a major crash risk factor but may be underrecognized as a risky driving behavior. Sleepy driving is usually rated as less of a road safety issue than more well-known risky driving behaviors, such as drink driving and ...
Armstrong, Kerry Ann, Watling, Christopher N., Smith, Simon S, Obst, Patricia L, Armstrong, Kerry A., Obst, Patricia L., Watling, Christopher N, Watling, Christopher N.,, Smith, Simon S.   +8 more
core   +2 more sources

Investigating the Effect of Performing Secondary Tasks on Reaction Time While Driving by Computer Analysis

Engineering Proceedings
Performing secondary tasks affects the performance of primary tasks. Engaging in secondary tasks while driving often leads to accidents. Therefore, this study aimed to investigate the impact on reaction time when drivers perform secondary tasks while ...
Chia-Wen Tsai, Dengchuan Cai
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source