Results 71 to 80 of about 3,045,870 (300)

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Cycling of biogenic elements drives biogeochemical gold cycling [PDF]

Earth-Science Reviews, 2019
Abstract Microorganisms are key-drivers of carbon-, nitrogen-, sulfur- and metal cycling on Earth. Through their metabolic activities they directly and indirectly link element cycles. This leads to the cycling of elements through the Earth’s ecosystems from/to the atmosphere to/from the lithosphere. Gold (Au) is a rare, redox-active, noble transition
Santonu Kumar Sanyal, Jeremiah Shuster, Frank Reith   +2 more
openaire   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Research status of hybrid electric vehicle energy management strategy based on the driving cycle

Journal of Hebei University of Science and Technology, 2016
The paper analyzes the advantages and disadvantages of two different energy management strategies which are the management strategy based on the dynamic system running state and the management strategy based on the driving cycle. The paper focuses on the
Xinyou LIN, Liuqing ZHAI, Haibo LIN
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Other title: Teen safe driving in Connecticut

, 2012
Annual; "Annual Report on Effectiveness of Connecticut's Teen Driving Laws.

core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Validating on-the-limit properties of a driving simulator

, 2014
The paper describes a validation model for both subjective and objective comparison of on-the-limit properties of a driving simulator. VTI moving base driving simulator, SIM III, has been used with three different versions of VTI’s vehicle model, for ...
Kharrazi, Sogol, Eriksson, Olle, Hjort, Mattias, Hjälmdahl, Magnus, Andersson Hultgren, Jonas   +4 more
core   +1 more source

Optimization Source Structure of Electric Vehicle Using Calculation of Energy Consumption in Matlab GUI

Advances in Electrical and Electronic Engineering, 2015
The capacity of the primary energy source is the main parameter participating in a range of the electric vehicle (EV). The final choice of an appropriate structure of sources integrated into the vehicle can consist of one or a variety of energy sources ...
Peter Cubon, Roman Radvan, Vladimir Vavrus   +2 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source