Results 71 to 80 of about 750,621 (312)

Unraveling climate and human drivers of vegetation productivity dynamics in Yunnan Province, China: a structural equation modeling approach with empirical orthogonal function analysis

International Journal of Digital Earth
Vegetation net primary productivity (NPP) serves as a critical indicator of ecosystem health and carbon sequestration capacity in ecologically fragile mountainous regions.
Jun Ma, Jinliang Wang, Suling He, Jianpeng Zhang, Lanfang Liu, Xuzhen Zhong   +5 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Review of Contributing Factors and Interventions for Dangerous Driving

Journal of Road Safety, 2015
This paper reviews published research relevant to understanding dangerous driving. A systematic search of relevant databases identified 117 papers that considered driving behaviour, but only 12 that specifically discuss factors that influence dangerous ...
Bianca Urquhart, Andrew Day, Gennady Baksheev   +2 more
doaj  

Analysis and Short-Term Peak Forecasting of the Driving Factors of Carbon Emissions in the Construction Industry at the Provincial Level in China

Energies
The construction industry plays a pivotal role in China’s achievement of its “dual carbon” goals. This study conducts a decomposition analysis of the carbon emissions from the construction industry (CECI) at both national and provincial levels for the ...
Chao Dai, Yuan Tan, Shuangping Cao, Hong Liao, Jie Pu, Haiyan Huang, Weiguang Cai   +6 more
doaj   +1 more source

Predicting Scientific Evolution by Understanding its Driving Factors

, 2018
Presentation for the 2018 International Conference on Knowledge Management. This presentation focuses on building a quantitative understanding of key factors driving scientific ...
He, Jiangen
core  

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

An Examination of the Spatial Distribution Patterns of National-Level Tourism and Leisure Districts in China and Their Underlying Driving Factors

Buildings
In recent years, tourism and leisure districts have become a pivotal aspect of China’s tourism development. Analyzing their spatial distribution characteristics and driving factors is essential for fostering comprehensive district tourism and promoting ...
Shuangqing Sheng, Huanli Pan, Lei Ning, Zhongqian Zhang, Qiuli Xue   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Glacial Waters Under Threat: Risk Assessment and Source Identification of Polychlorinated Biphenyls in Meili Snow Mountains, Southeastern Tibetan Plateau

Toxics
Polychlorinated biphenyls (PCBs) are classified as persistent organic pollutants (POPs) due to their potential threat to both ecosystems and human health.
Huawei Zhang, Yan Yao, Xinyu Wen, Rui Zhang, Rui Liu   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source