Results 41 to 50 of about 182,013 (307)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Unveiling the driving forces affecting carbon dioxide emissions in the Philippines | JBES 2023

open access: yes, 2023
Human-induced carbon dioxide emissions are the major cause of climate change. Although the Philippines’ contribution to global climate change due to carbon emissions is negligible, the trend of carbon emissions from the energy sector is increasing, with ...
Gracielle Rose D. Gentallan   +3 more
core   +1 more source

Barreras y fuerzas impulsoras de la implementación de la Industria 4.0 en las organizaciones: un estado del arte

open access: yesRevista de Investigación, Desarrollo e Innovación, 2021
Industry 4.0 is a manufacturing concept that has gained strength in organizations because it delves into industrial automation, digitization, and new technology implementation to improve working conditions and productivity.
Omar Alexánder León-García   +1 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Driving forces of the Swiss output gap [PDF]

open access: yes, 2011
Contrary to standard agnostic statistical approaches an output gap estimate based on a New Keynesian Small Open Economy model provides the possibility to analyze the driving forces of the variation in GDP caused by nominal rigidities.
Leist, Stefan
core  

Constraints and Driving Forces in Economic Systems

open access: yesKöz-gazdaság, 2020
Néhány évvel ezelőtt a BUKSZ egyik szerkesztőségi ülésén – éppen egy Festschrift bemutatásának esélyeit taglaltuk – valaki felvetette, hogy íratni kellene egy cikket a műfajról. Kik és miért készítenek, kik kapnak ilyen kiadványt?
Mihály Laki
doaj  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Forces driving epithelial wound healing

open access: yes, 2014
A fundamental feature of multicellular organisms is their ability to self-repair wounds through the movement of epithelial cells into the damaged area. This collective cellular movement is commonly attributed to a combination of cell crawling and 'purse ...
Gupta, Makund   +3 more
core   +1 more source

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