Results 241 to 250 of about 4,356,687 (302)

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

open access: yesFEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez   +4 more
wiley   +1 more source
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Chromatin Mechanisms Driving Cancer

Cold Spring Harbor Perspectives in Biology, 2021
The change in cell state from normal to malignant is driven fundamentally by oncogenic mutations in cooperation with epigenetic alterations of chromatin. These alterations in chromatin can be a consequence of environmental stressors or germline and/or somatic mutations that directly alter the structure of chromatin machinery proteins, their levels, or ...
Berkley, Gryder   +3 more
openaire   +2 more sources

SNOWMOBILE DRIVE MECHANISMS

2017
<div class="section abstract"> <div class="htmlview paragraph">This SAE Recommended Practice is applicable to snowmobiles as defined in SAE J33.</div> </div>
  +5 more sources

Mechanical drive control

Proceedings of the Institution of Mechanical Engineers, Part I: Journal of Systems and Control Engineering, 1999
Abstract Mechanical drives, for weapon platforms, comprising relatively long shafts with inertia discs, representing the motor armature, gearing, platform and load inertias, etc., are considered. Analysis procedures are employed to model a system which has driving and braking torque inputs.
R Whalley, D Mitchell, M Ebrahimi
openaire   +1 more source

Mechanics of the belt drive

International Journal of Mechanical Sciences, 1970
Abstract The mechanics of the belt drive is considered when the belt possesses a soft pliable envelope to grip the pulley and strong tension members to transmit the power. It is concluded that shear strains in the belt envelope are a large factor in determining drive behaviour.
openaire   +1 more source

Drive Mechanism and Controls

2020
Tapchangers are driven in normal operation by a drive mechanism. The mechanism may be integrally built as a part of the tapchanger or may be a separate physical entity. In the case of many compartment type tapchangers, the mechanism is built in. This is not a functional necessity.
openaire   +1 more source

Dynamics of a Mechanical Drive

1985
The equations derived in Chap. 1 $$J\frac{{d\omega }}{{dt}} = {{m}_{M}}\left( {\omega ,{\mkern 1mu} {\mkern 1mu} \varepsilon ,{\mkern 1mu} {\mkern 1mu} {{y}_{M}},{\mkern 1mu} {\mkern 1mu} t} \right) - {{m}_{L}}\left( {\omega ,{\mkern 1mu} {\mkern 1mu} \varepsilon ,{\mkern 1mu} {\mkern 1mu} {{y}_{L}},{\mkern 1mu} {\mkern 1mu} t} \right)$$ (2.1)
openaire   +1 more source

Study on the omnidirectional driving gear mechanism

2012 IEEE International Conference on Robotics and Automation, 2012
In this paper, the principles and the actual configurations of the omnidirectional driving gear mechanism that was implemented by the authors were described. The validity of the proposed structure was also confirmed and its basic characteristics understood through experiments using the actual prototypes.
Kenjiro Tadakuma   +7 more
openaire   +1 more source

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