Results 41 to 50 of about 116,832 (264)

Comparative Analysis of Driving Performance and Visual and Physiological Responses Between Professional and Civilian Drivers in Simulated Environments

Applied Sciences
Current research and development in understanding road users’ driving behaviors play a key role in improving traffic safety. Recently, several driving simulators have been employed as a suitable approach to investigate several drivers’ responses in ...
Viktor Nagy, Ágoston Pál Sándor, Gábor Kovács, Hanan Elias, Giuseppina Pappalardo   +4 more
doaj   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

User Interaction with Digital Twins for Driving: How Comparable Are Simulated and Real Trajectories?

Systems
This paper investigates the physiological responses of individuals driving both on a real route and within a vehicle simulator designed as a digital twin of that route.
Marcin Czaban, Eldar Sultanow, Alina Chircu, Christian Czarnecki, Joachim Riedl, Stefan Wengler   +5 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Predicting Perceived Realism in Virtual Reality Driving Simulations Using Participants’ Personality Traits, Heart Rate Changes, and Risk Preference

IEEE Access
Virtual reality (VR) has recently been adopted for driving simulations to enhance their realism and thus improve the validity of the simulation results. However, given that perceived realism is a subjective factor that varies by individual, understanding
Uijong Ju, Sanghyeon Kim
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Optimisation and Evaluation of a Fuzzy-Based One-Pedal Driving Strategy for Enhancing Energy Efficiency and Driving Comfort

World Electric Vehicle Journal
Electric Vehicles (EVs) are still facing prejudices about limited range, making them unattractive for many customers. However, their locally emission-free operation and the ability to recover kinetic energy during braking manoeuvres are significant ...
Tim Hammer, Thomas Mitsching, Marius Heydrich, Valentin Ivanov   +3 more
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Length Requirements for Urban Expressway Work Zones’ Warning and Transition Areas Based on Driving Safety and Comfort

Systems
As aging urban expressways become more pronounced, maintenance and construction work on these roadways is increasingly necessary. Some lanes may need to be closed during maintenance and construction, decreasing driving safety and comfort in the work zone.
Aixiu Hu, Ruiyun Huang, Yanqun Yang, Ibrahim El-Dimeery, Said M. Easa   +4 more
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source