Results 41 to 50 of about 3,693,461 (301)

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Validating on-the-limit properties of a driving simulator

open access: yes, 2014
The paper describes a validation model for both subjective and objective comparison of on-the-limit properties of a driving simulator. VTI moving base driving simulator, SIM III, has been used with three different versions of VTI’s vehicle model, for ...
Kharrazi, Sogol   +4 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Driving Vigilance Simulator Test

open access: yesActa Oto-Laryngologica, 1990
Drivers suffering from sleepiness at the wheel run the risk of being involved in car accidents. To evaluate whether objective data of driving performance can be assessed in patients with excessive tendency of falling asleep at the wheel, two test versions of a computerized driving program were created to fit an advanced driving simulator.
P O, Haraldsson   +3 more
openaire   +3 more sources

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Rolling out a new Driving Simulator Concept - Design and Challenges of Wheeled Mobile Driving Simulators

open access: yes, 2021
Wheeled mobile driving simulators (WMDS) intend to cue the motion of road vehicles by moving a tire-bound, electrically driven, omnidirectional platform.
Albrecht, Torben   +9 more
core  

A Training Oriented Driving Simulator [PDF]

open access: yes, 2007
In today's China, a growing number of people have the opportunity to have their own cars. This creates tremendous requirement of training of new drivers. At the same time, recent advances in Computer Graphics and Virtual Reality system have brought the new opportunities for the development of driving simulation. This paper describes a driving simulator
Chao Sun   +4 more
openaire   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

User Interaction with Digital Twins for Driving: How Comparable Are Simulated and Real Trajectories?

open access: yesSystems
This paper investigates the physiological responses of individuals driving both on a real route and within a vehicle simulator designed as a digital twin of that route.
Marcin Czaban   +5 more
doaj   +1 more source

Foggy perception slows us down

open access: yeseLife, 2012
Visual speed is believed to be underestimated at low contrast, which has been proposed as an explanation of excessive driving speed in fog. Combining psychophysics measurements and driving simulation, we confirm that speed is underestimated when contrast
Paolo Pretto   +3 more
doaj   +1 more source

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