Results 41 to 50 of about 122,807 (259)

Foggy perception slows us down

open access: yeseLife, 2012
Visual speed is believed to be underestimated at low contrast, which has been proposed as an explanation of excessive driving speed in fog. Combining psychophysics measurements and driving simulation, we confirm that speed is underestimated when contrast
Paolo Pretto   +3 more
doaj   +1 more source

Blueprint for a Simulation Framework to Increase Driver Training Safety in North America: Case Study

open access: yesSafety, 2021
Despite numerous recent advances in the classroom and in-vehicle driver training and education over the last quarter-century, traffic accidents remain a leading cause of mortality for young adults—particularly, those between the ages of 16 and 19 ...
Kevin F. Hulme   +13 more
doaj   +1 more source

A Training Oriented Driving Simulator [PDF]

open access: yes, 2007
In today's China, a growing number of people have the opportunity to have their own cars. This creates tremendous requirement of training of new drivers. At the same time, recent advances in Computer Graphics and Virtual Reality system have brought the new opportunities for the development of driving simulation. This paper describes a driving simulator
Chao Sun   +4 more
openaire   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

User Interaction with Digital Twins for Driving: How Comparable Are Simulated and Real Trajectories?

open access: yesSystems
This paper investigates the physiological responses of individuals driving both on a real route and within a vehicle simulator designed as a digital twin of that route.
Marcin Czaban   +5 more
doaj   +1 more source

New ideas on how drivers perceive speed emerge from the fog

open access: yeseLife, 2012
Experiments with a driving simulator contradict previous results by showing that car drivers slow down in fog. However, other forms of reduced visibility can cause drivers to speed up.
Jody C Culham
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Comparative Analysis of Driving Performance and Visual and Physiological Responses Between Professional and Civilian Drivers in Simulated Environments

open access: yesApplied Sciences
Current research and development in understanding road users’ driving behaviors play a key role in improving traffic safety. Recently, several driving simulators have been employed as a suitable approach to investigate several drivers’ responses in ...
Viktor Nagy   +4 more
doaj   +1 more source

Prediction of immediately occurring microsleep events from brain electric signals

open access: yesCurrent Directions in Biomedical Engineering, 2016
This contribution addresses the question if imminent changes of the cortical state are predictable. The analysis is based on 1484 examples of microsleep (MS) and 1940 counterexamples of sustained attention (SA), both observed during overnight driving in ...
Golz Martin   +2 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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