Results 51 to 60 of about 115,016,362 (287)

Dropping Bodies

The Mathematical Intelligencer, 2023
The subject is brake orbits for the 3-body problem: orbits where all velocities are zero at some instant. We extract a paradox and a mystery out of a recent database of 30 non-collision periodic brake orbits for the equal mass 3-body problem built up by Li and Liao. We solve the paradox and the mystery and pose an open question.
openaire   +6 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Relative, individualized, or normalized? A conceptual clarification of running speed terminology in soccer

Frontiers in Sports and Active Living
There is inconsistency in quantifying, defining and interpreting running speed nomenclature in soccer. In particular, the terms “relative”, “individualized”, and “normalized” are frequently used interchangeably, despite referring to different conceptual ...
Ricardo Pimenta, Ricardo Pimenta, Ricardo Pimenta, Ricardo Pimenta, Hugo Antunes, José Afonso, Fábio Yuzo Nakamura, Fábio Yuzo Nakamura, Fábio Yuzo Nakamura   +8 more
doaj   +1 more source

Neuromuscular Changes in Drop Jumps on Different Common Material Surfaces with Incremental Drop Heights

Applied Sciences, 2023
The purpose of this study was to compare changes in muscle pre-activation and short-latency responses in the lower limbs during drop jumps performed on different common soft and hard surfaces and at various platform heights.
Hsien-Te Peng, Hsiu-Kuang Chang, Hung-Wen Chen, Tsung-I Huang, Hui Chen   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Should GPS data be normalized for performance and fatigue monitoring in soccer? A theoretical-practical discussion on high-speed running

Frontiers in Sports and Active Living
High-speed running (HSR) is one of the performance metrics of interest, as the volume of HSR during matches has been increasing over the last decade, which suggests that weekly training loads should be adjusted to align with this trend, enabling players ...
Ricardo Pimenta, Ricardo Pimenta, Ricardo Pimenta, Ricardo Pimenta, Hugo Antunes, João Ribeiro, João Ribeiro, Fábio Yuzo Nakamura, Fábio Yuzo Nakamura   +8 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source