Results 61 to 70 of about 115,016,362 (287)
Social and Emotional Learning: Research, Practice, and PolicyDeveloping social-emotional training opportunities for caregivers and professionals can promote higher quality care for children and families in the home and in early years services.
Ruth Speidel +11 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
SportsChange-of-direction (COD) capacity is a key performance metric in football due to the high volume of COD actions occurring during match play. This study aimed to (i) evaluate the repeatability of the 5-0-5 test and (ii) examine the relationship between ...
Ricardo Pimenta +2 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
EnergiesHeat pump water heaters (HPWHs) are a proven technology for water heating that has been commercialized. The adoption of HPWHs for domestic and commercial water heating is growing rapidly because of their superior performance compared with alternative ...
Ahmed Elatar +4 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Case of unexplained progressive drop in vision
Indian Journal of Ophthalmology. Case ReportsWe report a rare case of an 80-year-old male, diabetic and hypertensive, with glaucoma in both eyes on medical management for 15 years with a best corrected visual acuity of 6/9, N6 in both eyes at presentation.
Bhavini Johri +2 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Obesity PillarsBackground: Nutritional deficiencies are common among people with obesity, before and during treatment, such as with very-low-calorie diets and metabolic/bariatric surgery.
Jaime P. Almandoz +9 more
doaj +1 more source
EPL (Europhysics Letters), 2018 Rigid superhydrophobic materials have the ability to repel millimetric water drops, in typically 10 ms. Yet, most natural water-repellent materials can be deformed by impacting drops. To test the effect of deformability, we perform impacts of non-wetting drops onto thin ($\sim$ 10 \micro m), circular PDMS membranes.
Chantelot, Pierre +3 more
openaire +3 more sources