Results 141 to 150 of about 500,205 (299)
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Surfactant‐mediated electro‐dewetting of droplets in oil for liquid‐shape manipulation
DropletThe capability to manipulate liquid shape at the microscale has enabled numerous microfluidic devices. Due to its simple electric actuation, electrowetting‐on‐dielectric has been widely used in a variety of microfluidic applications that require ...
Qining Leo Wang +2 more
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
An electrocyte‐inspired moisture‐driven electricity generator for self‐sustained water electrolysis
DropletHarvesting electricity from ubiquitous moisture offers the promise of clean power for self‐sustained systems. Despite extensive efforts, achieving high‐power electricity generation remains challenging.
Quanmao Wei +9 more
doaj +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Bubble pinch‐off on biphilic and superhydrophobic surfaces
DropletIn this work, we experimentally measured the pinch‐off of a gas bubble on a biphilic surface, which consisted of an inner circular superhydrophobic region and an outer hydrophilic region.
Hangjian Ling +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Phenomenological contact line friction coefficient
DropletAn important feature of contact line motion, as an irreversible process, is its dissipative nature, which can dominate the dynamics during the early stages of droplet spreading.
Jiaxing Shen +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source