Bioinspired materials for droplet manipulation: Principles, methods and applications
Droplet manipulation techniques such as transport and merging have been widely used in many fields including biology, chemistry, material and energy applications.
Jinkai Xu +4 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Actuating droplets with electrowetting: Force and dynamics
Electrowetting on dielectric (EWOD) allows rapid movement of liquid droplets on a smooth surface, with applications ranging from lab‐on‐chip devices to micro‐actuators. The in‐plane force on a droplet is a key indicator of EWOD performance.
Robert Hennig +2 more
doaj +1 more source
Thermocapillary flow‐induced core release from double‐emulsion droplets in microchannels
The use of double emulsions (DEs), which represent colloidal structures composed of droplets nested within droplets, can provide for unparallel droplet manipulation in droplet‐based microfluidic technology due to their unique core–shell structures.
Jingyi Qin +4 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Target slinging of droplets with a flexible cantilever
Control of the directional bounce of droplets impacting solid surfaces is crucial for many agricultural and industrial applications. However, for the universal impact process of raindrops on plant leaves, little is known about how the highly coupled and ...
Wei Fang +7 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Reproducible reformation of a bilayer lipid membrane using microair bubbles
Planar bilayer lipid membranes (BLMs) are widely used as models for cell membranes in various applications, including drug discovery and biosensors. However, the nanometer‐thick bilayer structure, assembled through hydrophobic interactions of amphiphilic
Izumi Hashimoto +6 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Programmable droplet manipulation enabled by charged‐surface pattern reconfiguration
Programmable droplet manipulation based on external stimulation is in high demand in various modern technologies. Despite notable progress, current manipulation strategies still suffer from a common drawback such as single control means of modulating the
Duokui Fang +6 more
doaj +1 more source

