Results 41 to 50 of about 6,322 (255)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Micromachines, 2019 Gallium-based liquid metal alloys have been attracting attention from both industry and academia as soft, deformable, reconfigurable and multifunctional materials in microfluidic, electronic and electromagnetic devices. Although various technologies have
Ming Li +4 more
doaj +1 more source
Nanomaterials, 2020 We investigate the quantum confinement effects on excitons in several types of strain-free GaAs/Al 0.3 Ga 0.7 As droplet epitaxy (DE) quantum dots (QDs).
Inah Yeo +6 more
doaj +1 more source
Fabrication of Microparticles with Front–Back Asymmetric Shapes Using Anisotropic Gelation
Micromachines, 2021 Droplet-based microfluidics is a powerful tool for producing monodispersed micrometer-sized droplets with controlled sizes and shapes; thus, it has been widely applied in diverse fields from fundamental science to industries.
Dongkyu Lee +2 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Two-dimensional quantum droplets in dipolar Bose gases
New Journal of Physics, 2019 We calculate analytically the quantum and thermal fluctuations corrections of a dilute quasi-two-dimensional Bose-condensed dipolar gas. We show that these fluctuations may change their character from repulsion to attraction in the density-temperature ...
Abdelâali Boudjemâa
doaj +1 more source
Highly uniform GaSb quantum dots with indirect–direct bandgap crossover at telecom range
APL Materials, 2021 We demonstrate a new quantum-confined semiconductor material based on GaSb quantum dots (QDs) embedded in a single-crystalline AlGaSb matrix by filling droplet-etched nanoholes.
Abhiroop Chellu +3 more
doaj +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source