Results 51 to 60 of about 867,533 (280)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Single droplet experimentation on spray drying:evaporation of sessile droplets deposited on a flat surface [PDF]

, 2010
: Individually dispensed droplets were dried on a flat surface to mimic the drying of single droplets during spray drying. A robust dispensing process is presented that generates small droplets (dp>150 µm).
Fox, M.B., Perdana, J.A., Schutyser, M.A.I., Boom, R.M.   +3 more
core  

Distribution Characteristics of Rotor Airflow and Droplet Deposition of Plant Protection UAVs Under Varying Rotor–Nozzle Distances

Agriculture
The rotor airflow intensity and distribution characteristics of plant protection UAVs vary significantly with spatial positions below the rotor. Consequently, changes in the rotor–nozzle distance directly affect droplet motion and deposition patterns. To
Xiaojie Xu, Shengde Chen, Zhihong Li, Zehong Wu, Yuxiang Tan, Shimin Huang, Yubin Lan   +6 more
doaj   +1 more source

Effect of UAV prewetting application during the flowering period of cotton on pesticide droplet deposition [PDF]

Frontiers of Agricultural Science and Engineering, 2018
Prewetting process can reduce the contact angle between the droplet and the leaf blade, so that the droplet can more easily wet and spread, thereby increasing the quantity of deposition.
Weixiang YAO, Xianju WANG, Yubin LAN, Ji JIN
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Study on Spray Deposition Effect of a New High-Clearance Air-Assisted Electrostatic Sprayer

Agriculture
This study evaluates the performance of a novel high-clearance air-assisted electrostatic sprayer designed for vineyards and investigates the impact of applied voltage on droplet deposition.
Mingxiong Ou, Shiqun Dai, Xinbao Jing, Weidong Jia, Xiang Dong, Yunfei Wang, Minmin Wu   +6 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Research on a UAV spray system combined with grid atomized droplets

Frontiers in Plant Science
BackgroundsUAVs for crop protection hold significant potential for application in mountainous orchard areas in China. However, certain issues pertaining to UAV spraying need to be addressed for further technological advancement, aimed at enhancing crop ...
Xiuyun Xue, Xiuyun Xue, Xiuyun Xue, Xiuyun Xue, Yu Tian, Zhenyu Yang, Zhen Li, Zhen Li, Zhen Li, Zhen Li, Shilei Lyu, Shilei Lyu, Shilei Lyu, Shilei Lyu, Shuran Song, Shuran Song, Shuran Song, Daozong Sun, Daozong Sun, Daozong Sun   +19 more
doaj   +1 more source