Results 81 to 90 of about 3,583,136 (389)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Study on the behavior of small droplet impinging onto a hot surface [PDF]

, 2011
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
3rd Micro and Nano Flows Conference (MNF2011), Arita, M, Fukuda, S, Hidaka, S, Ishihara, N, Kohno, M, Tagashira, K, Takata, Y   +7 more
core   +1 more source

Slip or not slip? A methodical examination of the interface formation model using two-dimensional droplet spreading on a horizontal planar substrate as a prototype system

, 2012
We consider the spreading of a thin two-dimensional droplet on a planar substrate as a prototype system to compare the contemporary model for contact line motion based on interface formation of Shikhmurzaev [Int. J. Multiphas.
David N. Sibley, Navier C.-L., Nikos Savva, Serafim Kalliadasis, Shikhmurzaev Y. D., Slattery J. C.   +5 more
core   +1 more source

Blended E85-diesel fuel droplet heating and evaporation [PDF]

, 2019
The multidimensional quasi-discrete (MDQD) model is applied to the analysis of heating and evaporation of mixtures of E85 (85 vol % ethanol and 15 vol % gasoline) with diesel fuel, commonly known as “E85–diesel” blends, using the universal quasi-chemical
Al Qubeissi, Mansour, Al-Esawi, Nawar Hasan Imran, Sazhin, Sergei S., Whitaker, Reece   +3 more
core   +2 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Material Issues in Layered Forming [PDF]

, 1993
A brief overview of key issues in layered thermal processing is given. Incremental sintering and layered fusion ofpowder and molten droplets are discussed.
Amon, Christina, Beuth, Jack, Kirchner, Helmut, Merz, Robert, Prinz, Fritz, Schmaltz, Kevin, Weiss, Lee   +6 more
core   +1 more source

Droplet Transfer in Two-Phase Annular Mist Flow : Part 1, Experiment of Droplet Transfer Rate and Distributions of Droplet Concentration and Velocity

Bulletin of JSME, 1972
The experimental results are described on the transfer rate of liquid droplet onto the duct wall, the distributions of the droplet volumetric fraction, the droplet and gas velocities, and the pressure loss for a two-phase (Air-water) annular mist flow through a horizontal rectangular duct.
Sadahiro NAMIE, Tatsuhiro UEDA
openaire   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Acoustic Attenuation in Fans and Ducts by Vaporization of Liquid Droplets [PDF]

, 1975
A cloud of small water droplets in saturated air attenuates acoustic disturbances by viscous drag, heat transfer, and vapor exchange with the ambient gas. The viscous and heat transfer phenomena attenuate at frequencies above 104 Hz for I-J.l droplets.
Candel, Sebastien M., Marble, Frank E.
core  

Topologically Protected Quantum State Transfer in a Chiral Spin Liquid [PDF]

, 2011
Topology plays a central role in ensuring the robustness of a wide variety of physical phenomena. Notable examples range from the robust current carrying edge states associated with the quantum Hall and the quantum spin Hall effects to proposals ...
A Micheli, A Sommerfeld, AV Gorshkov, AY Kitaev, C Nayak, C Vieu, C Zhang, D Gottesman, D Marcos, DM Toyli, E Dennis, FG Paauw, FY Zhang, G Balasubramanian, H Yao, HP Buchler, IL Chuang, J Bylander, J Majer, J Preskill, J Sherson, J Twamley, JA Stroscio, JJL Morton, JM Taylor, JQ You, JQ You, K Gomes, L Balents, L Fu, LM Duan, M Christandl, M Hermele, M Kohmoto, MA Sillanpaa, MD Lukin, MD Reed, MVG Dutt, MW Johnson, NY Yao, NY Yao, P Fendley, P Neumann, PA Lee, PC Maurer, R Harris, R Islam, S Bose, T Monz, T Osborne, X Zhu, X-L He, Y Machida, Z Kurucz   +53 more
core   +3 more sources