Results 191 to 200 of about 215,422 (309)

A Robust Deep Temporal Causal Discovery Platform for Single‐Cell Gene Regulatory Network Reconstruction

Advanced Intelligent Discovery, EarlyView.
scTIGER2.0 is a deep‐learning framework that infers gene regulatory networks from single‐cell RNA sequencing data. By integrating correlation, pseudotime ordering, deep learning and bootstrap‐based significance testing, it reduces false positives and reveals directional gene interactions.
Nishi Gupta, Madison Dautle, Shaoqiang Zhang, Yong Chen   +3 more
wiley   +1 more source

Holding the treatment frame: borderline features, personality functioning, and psychotherapy dropout in a youth mental health service. [PDF]

Res Psychother
De Salve F, Rossi C, Oasi O, Malvini L, Meliante M, Percudani M, Messina I.   +6 more
europepmc   +1 more source

Multi‐Property Machine Learning Models to Accelerate the Transition Toward Bio‐Based Emulsion Polymers

Advanced Intelligent Discovery, EarlyView.
A machine learning framework simultaneously predicts four critical properties of monomers for emulsion polymerization: propagation rate constant, reactivity ratios, glass transition temperature, and water solubility. These tools can be used to systematically identify viable bio‐based monomer pairs as replacements for conventional formulations, with ...
Kiarash Farajzadehahary, Nicholas Ballard   +1 more
wiley   +1 more source

Effectiveness of the Functional-Cognitive and Sensory Treatment for Improving Daily Functioning of Individuals with Substance Use Disorder: A Randomized Controlled Trial. [PDF]

Subst Abuse Rehabil
Assayag N, Bachar Kirshenboim Y, Nemesh-Godin T, Zaude R, Rand D, Bar Shalita T.   +5 more
europepmc   +1 more source

AI‐Driven Cancer Multi‐Omics: A Review From the Data Pipeline Perspective

Advanced Intelligent Discovery, EarlyView.
The exponential growth of cancer multi‐omics data brings opportunities and challenges for precision oncology. This review systematically examines AI's role in addressing these challenges, covering generative models, integration architectures, Explainable AI for clinical trust, clinical applications, and key directions for clinical translation.
Shilong Liu, Shunxiang Li, Kun Qian
wiley   +1 more source

Odocoileus virginianus PRNP sequencing reveals AF (Q₉₅G₉₆/H₉₅G₉₆) advantage over AC (Q₉₅G₉₆/Q₉₅S₉₆) against chronic wasting disease. [PDF]

Vet Res
London EW, Roca AL, Ishida Y, Latif T, Novakofski JE, Mateus-Pinilla NE.   +5 more
europepmc   +1 more source

AS‐pHopt: An Optimal pH Prediction Model Enhanced by Active Site of Enzymes

Advanced Intelligent Discovery, EarlyView.
To address the low accuracy of enzyme optimal pH (pHopt) prediction, this study develops active site‐based pHopt (AS‐pHopt), a prediction model enhanced by active site information and pseudo‐label prediction. Integrating key structural and physicochemical features affecting enzyme pHopt, AS‐pHopt uses Evolutionary Scale Modeling (ESM)‐2 with active ...
Wenxiang Song, Xinmin Li, Hongbo Yu, Le Xiong, Guixia Liu, Weihua Li, Yun Tang   +6 more
wiley   +1 more source

Dropout in supervised small-group exercise programs: a 7-year retrospective cohort study. [PDF]

Front Public Health
da Silva CER, de Jesus Santana W, Morales V, Pinto LG, Leme G, Doro AR, Lima L, Jung ME, Junior AF.   +8 more
europepmc   +1 more source

Machine‐Learning‐Assisted Onset‐Time Determination in Transient Luminescence Thermometry

Advanced Intelligent Discovery, EarlyView.
Artificial neural networks enable autonomous extraction of onset times from transient heating curves in luminescence thermometry. Using Ln3+‐doped upconverting nanoparticles as luminescent thermometers, we combine experimental transients with physically motivated synthetic curves to enhance data diversity and improve generalization.
David J. Sousa, Erving Ximendes, Luís D. Carlos, Carlos D. S. Brites   +3 more
wiley   +1 more source

Socioeconomic inequality in second-dose measles vaccination dropout among children aged 15-35 months in East Africa: A decomposition analysis of a recent Demographic Health Survey. [PDF]

Hum Vaccin Immunother
Molla Lakew A, Limenih MA, Belew AK, Muhammad EA, Beshaw MA, Angaw DA.   +5 more
europepmc   +1 more source