Results 181 to 190 of about 85,546 (299)

The safety and efficacy of human umbilical cord mesenchymal stem cell for acute respiratory distress syndrome: an open-label and multicenter phase 1 clinical trial. [PDF]

Front Immunol
Ge Q, Zheng L, Zhao M, Li C, Zhao Z, Wang Z, Zhang Q, Shi M, Li Y, Zhang J, Qiao Y, Wei S, Shen N, Long H, Liu Y, Qiao J.   +15 more
europepmc   +1 more source

A Robust Deep Temporal Causal Discovery Platform for Single‐Cell Gene Regulatory Network Reconstruction

Advanced Intelligent Discovery, EarlyView.
scTIGER2.0 is a deep‐learning framework that infers gene regulatory networks from single‐cell RNA sequencing data. By integrating correlation, pseudotime ordering, deep learning and bootstrap‐based significance testing, it reduces false positives and reveals directional gene interactions.
Nishi Gupta, Madison Dautle, Shaoqiang Zhang, Yong Chen   +3 more
wiley   +1 more source

Beyond the tip of the iceberg: quantifying the odds of multidrug-resistance carriers for receiving post-acute follow-up rehabilitation after hospital stay - a real-world study using German data. [PDF]

BMJ Public Health
Kaba HEJ, Wenzlaff-Lodge P, Scheithauer S.   +2 more
europepmc   +1 more source

Multi‐Property Machine Learning Models to Accelerate the Transition Toward Bio‐Based Emulsion Polymers

Advanced Intelligent Discovery, EarlyView.
A machine learning framework simultaneously predicts four critical properties of monomers for emulsion polymerization: propagation rate constant, reactivity ratios, glass transition temperature, and water solubility. These tools can be used to systematically identify viable bio‐based monomer pairs as replacements for conventional formulations, with ...
Kiarash Farajzadehahary, Nicholas Ballard   +1 more
wiley   +1 more source

Effectiveness of monitoring mechanisms in reducing immunization dropouts among infants in health facilities of Maridi County, South Sudan. [PDF]

PLoS One
Igga DOM, Mwita N, Muni K.
europepmc   +1 more source

AI‐Driven Cancer Multi‐Omics: A Review From the Data Pipeline Perspective

Advanced Intelligent Discovery, EarlyView.
The exponential growth of cancer multi‐omics data brings opportunities and challenges for precision oncology. This review systematically examines AI's role in addressing these challenges, covering generative models, integration architectures, Explainable AI for clinical trust, clinical applications, and key directions for clinical translation.
Shilong Liu, Shunxiang Li, Kun Qian
wiley   +1 more source

DiST: disentangling structure via self-supervised tensors for heterophilous spatial transcriptomics. [PDF]

Brief Bioinform
Liu Y, Hu Y, Liu J, Tan S, Li X, Huang G, Chen M, Lei L, Du J.   +8 more
europepmc   +1 more source

AS‐pHopt: An Optimal pH Prediction Model Enhanced by Active Site of Enzymes

Advanced Intelligent Discovery, EarlyView.
To address the low accuracy of enzyme optimal pH (pHopt) prediction, this study develops active site‐based pHopt (AS‐pHopt), a prediction model enhanced by active site information and pseudo‐label prediction. Integrating key structural and physicochemical features affecting enzyme pHopt, AS‐pHopt uses Evolutionary Scale Modeling (ESM)‐2 with active ...
Wenxiang Song, Xinmin Li, Hongbo Yu, Le Xiong, Guixia Liu, Weihua Li, Yun Tang   +6 more
wiley   +1 more source

Long term effects of social stigma, career optimism, community disorder, and community ties on depressive symptoms among adolescent school dropouts. [PDF]

BMC Psychol
Kim YJ, Bae SM.
europepmc   +1 more source

Machine‐Learning‐Assisted Onset‐Time Determination in Transient Luminescence Thermometry

Advanced Intelligent Discovery, EarlyView.
Artificial neural networks enable autonomous extraction of onset times from transient heating curves in luminescence thermometry. Using Ln3+‐doped upconverting nanoparticles as luminescent thermometers, we combine experimental transients with physically motivated synthetic curves to enhance data diversity and improve generalization.
David J. Sousa, Erving Ximendes, Luís D. Carlos, Carlos D. S. Brites   +3 more
wiley   +1 more source