Results 221 to 230 of about 752,872 (357)

Focused Ultrasound‐Induced Mechanical Ablation Affects the Carbohydrate Metabolism of Residual/Peri‐Focally Localized Glioblastoma Cells

open access: yesInternational Journal of Cancer, EarlyView.
Glioblastoma (GBM) is highly aggressive and therapy‐resistant, warranting exploration of novel treatment strategies, among them mechanical high‐intensity focused ultrasound (mFUS), which holds significant promise for tumor ablation. The present study examined mFUS‐induced changes specifically in carbohydrate metabolism, which affects vulnerability to ...
Frieda Bayler   +10 more
wiley   +1 more source

Beyond Tradition: An Integrated Toxicological, Ecological, and Public Health Perspective on Aristolochic Acids

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza   +2 more
wiley   +1 more source

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy   +7 more
wiley   +1 more source

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

Multiple-Pathway Analysis of Double-Strand Break Repair Mutations in Drosophila

open access: gold, 2007
Dena M. Johnson-Schlitz   +2 more
openalex   +2 more sources

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