Trapped in the web: network architectures spread coevolution and shape adaptation
Adaptation is critical for biodiversity to persist under global change. Within ecological communities, species often face tradeoffs between adapting to shifting abiotic conditions and navigating the complex selective pressures imposed by interaction networks.
Alexandre Fuster‐ Calvo +5 more
wiley +1 more source
Targeting the integrated stress response or Ataxin-2 alleviates neurodegeneration in PolyGR models of C9orf72 associated frontotemporal dementia and amyotrophic lateral sclerosis. [PDF]
Harper NS +12 more
europepmc +1 more source
Ankh‐Score Produces Better Sequence Alignments Than AlphaFold3
ABSTRACT Protein sequence alignment is one of the most fundamental procedures in bioinformatics. Due to its many downstream applications, improvements to this procedure are of great importance. We consider two revolutionary concepts that emerged recently as candidates for improving the state‐of‐the‐art alignment methods: AlphaFold and protein language ...
Julia Malec +3 more
wiley +1 more source
Chlorophyll Supplementation Delays Aging in <i>Drosophila melanogaster</i> via Enhanced Stress Resistance and Detoxification Network Remodeling. [PDF]
Shen S +6 more
europepmc +1 more source
RNA degradomics revealed dsProsβ1‐derived siRNA‐mediated mRNA cleavage events, mainly at uracil‐guanine and adenine‐adenine pairs. Proteasome inhibition via dsProsβ1 increased mitochondrial and cytoskeletal proteins while reducing translation‐related and mRNA‐binding proteins.
Doga Cedden +3 more
wiley +1 more source
The histone gene family in <i>Drosophila simulans</i> carries consistent species-specific nucleotide polymorphisms distinct from that of <i>Drosophila melanogaster</i>. [PDF]
Falcone S, Weber A, Awad S, Rieder L.
europepmc +1 more source
Chitosan/tripolyphosphate/double‐stranded RNA (dsRNA) nanoparticles enhance RNA interference efficacy of orally delivered dsRNA against Helicoverpa armigera. Nanoparticles reduce the LC50 and do not cause deleterious effects or toxicity on beneficial insects.
Daniel DN Vasquez +12 more
wiley +1 more source
Protocol for using an ELISA to detect total α-synuclein levels in Drosophila melanogaster lines expressing human α-synuclein point mutations. [PDF]
Sciortino M +3 more
europepmc +1 more source
Starvation stress significantly affected the growth and development of Hippodamia variegata. Combined transcriptome and metabolome analysis and RNA interference verification revealed that HvarAKR1B1 may be involved in the response of Hippodamia variegata to starvation stress.
Bing‐mei Song +5 more
wiley +1 more source
Host plant nutrition drives fitness outcomes in the cactus specialist Drosophila mettleri. [PDF]
Noronha L, Lazzaro BP, O'Grady PM.
europepmc +1 more source

