Continuous muscle, glial, epithelial, neuronal, and hemocyte cell lines for Drosophila research
eLife, 2023 Expression of activated Ras, RasV12, provides Drosophila cultured cells with a proliferation and survival advantage that simplifies the generation of continuous cell lines.
Nikki Coleman-Gosser +11 more
doaj +1 more source
A biogenic amine and a neuropeptide act identically: tyramine signals through calcium in drosophila tubule stellate cells [PDF]
, 2013 Insect osmoregulation is subject to highly sophisticated endocrine control. In Drosophila, both Drosophila kinin and tyramine act on the Malpighian (renal) tubule stellate cell to activate chloride shunt conductance, and so increase the fluid production ...
Cabrero P +9 more
core +1 more source
Circadian Rhythm Abnormalities in Parkinson's Disease from Humans to Flies and Back [PDF]
, 2018 Clinical and research studies have suggested a link between Parkinson\u2019s disease (PD) and alterations in the circadian clock. Drosophila melanogaster may represent a useful model to study the relationship between the circadian clock and PD.
Bisaglia, Marco +3 more
core +1 more source
Macrophage-derived upd3 Cytokine causes impaired glucose homeostasis and reduced lifespan in drosophila fed a lipid-rich diet [PDF]
, 2014 Long-term consumption of fatty foods is associated with obesity, macrophage activation and inflammation, metabolic imbalance, and a reduced lifespan. We took advantage of Drosophila genetics to investigate the role of macrophages and the pathway(s) that ...
Dionne, MS +5 more
core +1 more source
The impact of SPARC on age-related cardiac dysfunction and fibrosis in Drosophila [PDF]
, 2018 Tissue fibrosis, an accumulation of extracellular matrix proteins such as collagen, accompanies cardiac ageing in humans and this is linked to an increased risk of cardiac failure.
Hartley, Paul S. +3 more
core +1 more source
The natverse, a versatile toolbox for combining and analysing neuroanatomical data
eLife, 2020 To analyse neuron data at scale, neuroscientists expend substantial effort reading documentation, installing dependencies and moving between analysis and visualisation environments.
Alexander Shakeel Bates +6 more
doaj +1 more source
Cell Death and Disease, 2021 Polyglutamine (polyQ) diseases comprise Huntington’s disease and several subtypes of spinocerebellar ataxia, including spinocerebellar ataxia type 3 (SCA3).
Zhefan Stephen Chen +3 more
doaj +1 more source
Neural Representations of Courtship Song in the Drosophila Brain [PDF]
, 2012 Acoustic communication in drosophilid flies is based on the production and perception of courtship songs, which facilitate mating. Despite decades of research on courtship songs and behavior in Drosophila, central auditory responses have remained ...
, +4 more
core +2 more sources
Assaying locomotor activity to study circadian rhythms and sleep parameters in Drosophila. [PDF]
, 2010 Most life forms exhibit daily rhythms in cellular, physiological and behavioral phenomena that are driven by endogenous circadian (≡24 hr) pacemakers or clocks. Malfunctions in the human circadian system are associated with numerous diseases or disorders.
Chiu, Joanna C +4 more
core +3 more sources
Visualizing septins in early Drosophila embryos [PDF]
Methods in Cell Biology, Elsevier, 2016, Septins, 136, pp.183, 2016 Functional studies in Drosophila have been key for establishing a role for the septin family of proteins in animal cell division and thus extending for the first time observations from the budding yeast to animal cells. Visualizing the distribution of specific septins in different Drosophila tissues and, in particular, in the Drosophila embryo ...
arxiv +1 more source