Suppression of polyglutamine toxicity by a Drosophila homolog of myeloid leukemia factor 1 [PDF]
, 2002 The toxicity of an abnormally long polyglutamine [poly(Q)] tract within specific proteins is the molecular lesion shared by Huntington's disease (HD) and several other hereditary neurodegenerative disorders.
Benzer, Seymour, Kazemi-Esfarjani, Parsa
core +1 more source
Experimental Control and Characterization of Autophagy in Drosophila [PDF]
, 2008 Insects such as the fruit fly Drosophila melanogaster, which fundamentally reorganize their body plan during metamorphosis, make extensive use of autophagy for their normal development and physiology.
A.D. Velentzas +18 more
core +1 more source
Mycobiota, neuro-cognitif disorders and behavioural impairments: is there a relationship?
European Psychiatry, 2023 Introduction The human body carries large and diverse communities of symbiotic microbes that are important for human health and development. While the impact of the bacterial microbiota, which are mostly found in the human gut, on host physiology is ...
B. Abdelmoula +4 more
doaj +1 more source
Multifractal analysis of the long-range correlations in the cardiac dynamics of Drosophila melanogaster [PDF]
Chaos, Solitons and Fractals, vol. 28, p.p. 768-775 (2006), 2005 Time series of heartbeat activity of humans can exhibit long-range correlations. In this paper we show that such kind of correlations can exist for the heartbeat activity of much simpler species like Drosophila melanogaster. By means of the method of multifractal detrended fluctuation analysis (MFDFA) we calculate fractal spectra $f(\alpha)$ and $h(q)$
arxiv +1 more source
Cell lineage tracing reveals the plasticity of the hemocyte lineages and of the hematopoietic compartments in Drosophila melanogaster [PDF]
, 2010 Much of our knowledge on hematopoiesis, hematopoietic compartments, hematopoietic cell lineages and immunity has been derived from studies on the vertebrate immune system.
Brehélin +33 more
core +1 more source
Systematic image‐driven analysis of the spatial Drosophila embryonic expression landscape
Molecular Systems Biology, 2010 Discovery of temporal and spatial patterns of gene expression is essential for understanding the regulatory networks and development in multicellular organisms.
Erwin Frise +2 more
doaj +1 more source
Pooled genome-wide CRISPR activation screening for rapamycin resistance genes in Drosophila cells
eLife, 2023 Loss-of-function and gain-of-function genetic perturbations provide valuable insights into gene function. In Drosophila cells, while genome-wide loss-of-function screens have been extensively used to reveal mechanisms of a variety of biological processes,
Baolong Xia +4 more
doaj +1 more source
p120 catenin is required for the stress response in Drosophila [PDF]
, 2013 p120ctn is a ubiquitously expressed core component of cadherin junctions and essential for vertebrate development. Surprisingly, Drosophila p120ctn (dp120ctn) is dispensable for adherens junctions and development, which has discouraged Drosophila ...
Bauer, Christin +2 more
core +3 more sources
Modeling ADHD in Drosophila: Investigating the Effects of Glucose on Dopamine Production Demonstrated by Locomotion [PDF]
arXiv, 2021 Hyperactivity is one of the hallmakrs of ADHD. Aberrant dopamine signaling is a major theme in ADHD and dopamine production is directly linked to the intensity and persistence of hyperactive conduct. The strength and persistence of hyperactivity responses in Drosophila to startle stimuli were measured in a study to determine the effects of sugar on ...
arxiv
A Novel Method for Primary Blood Cell Culturing and Selection in Drosophila melanogaster
Cells, 2022 The blood cells of the fruit fly Drosophila melanogaster show many similarities to their vertebrate counterparts, both in their functions and their differentiation.
Enikő Kúthy-Sutus +5 more
doaj +1 more source