Results 51 to 60 of about 463,523 (298)
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Phytomedicine Plus, 2021 Background: Parkinson's Disease (PD) is characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta of the mid brain which leads to the depletion of dopamine levels.
Yasir Hasan Siddique +4 more
doaj +1 more source
Current Opinion in Neurobiology, 2015 The dissection of the Drosophila auditory system has revealed multiple parallels between fly and vertebrate hearing. Recent studies have analyzed the operation of auditory sensory cells and the processing of sound in the fly's brain. Neuronal responses to sound have been characterized, and novel classes of auditory neurons have been defined; transient ...
Albert, JT, Göpfert, MC
openaire +4 more sources
Transplantation in Drosophila [PDF]
Proceedings of the National Academy of Sciences, 1935 The application of the method of transplantation, which has been so fruitful in the study of many biological problems, to genetically well known material, has advantages which are at once apparent to those who have thought about questions concerning the relation of genes to the developmental process.
G W, Beadle, B, Ephrussi
openaire +2 more sources
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Genome Biology, 2007 A report of the 48th Annual Drosophila Research Conference, Philadelphia, USA, 7-11 March 2007.
Celniker, Susan E., Hoskins, Roger A.
openaire +4 more sources
Design and construction of a new Drosophila species, D.synthetica, by synthetic regulatory evolution [PDF]
, 2011 Here, I merge the principles of synthetic biology^1,2^ and regulatory evolution^3-11^ to create a new species^12-15^ with a minimal set of known elements.
Moreno, Eduardo, Eduardo Moreno
core +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
BioTechniquesGene expression assays that are based on quantitative real-time PCR (qRT-PCR) method are still very popular, therefore, we developed qDATA, an open-source R-based bioinformatics application that offers a quick and intuitive analysis of raw cycle ...
Adrian Ionascu +3 more
doaj +1 more source
Journal of Basic and Applied Zoology, 2018 Background Arecoline (an alkaloid) has been reported as a potent cytotoxic as well as genotoxic agent but its neurotoxic effects are limited. Material and methods In the present study, we evaluated the neurotoxic effects and changes in life cycle ...
Barkha Shakya, Yasir Hasan Siddique
doaj +1 more source