Results 61 to 70 of about 463,523 (298)

In the quest for the ideal sweetener: Aspartame exacerbates selected biomarkers in the fruit fly (Drosophila melanogaster) model of Alzheimer's disease more than sucrose

Aging Brain, 2023
This study evaluated the effect of dietary inclusions of aspartame and sucrose on some selected behavioral and biochemical indices linked with Alzheimer's disease in a transgenic fruit fly (Drosophila melanogaster) model expressing human amyloid ...
Bukola Christiana Adedayo, Stephanie Tolulope Akinniyi, Opeyemi Babatunde Ogunsuyi, Ganiyu Oboh   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A novel insertional allele of the CG18135 gene is associated with severe mutant phenotypes in Drosophila melanogaster

Frontiers in Genetics
Drosophila melanogaster has been at the forefront of genetic studies and biochemical modeling for over a century. Yet, the functions of many genes are still unknown, mainly because no phenotypic data are available.
Attila Cristian Ratiu, Attila Cristian Ratiu, Adrian Ionascu, Adrian Ionascu, Alexandru Al. Ecovoiu   +4 more
doaj   +1 more source

Drosophila myogenesis [PDF]

Current Biology, 2016
The skeletal muscle system is the largest organ in motile animals, constituting between 35 and 55% of the human body mass, and up to 75% of the body mass in flying organisms like Drosophila. The flight muscles alone in flying insects comprise up to 65% of total body mass.
Ingo, Bothe, Mary K, Baylies
openaire   +2 more sources

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Microwave-assisted synthesis, characterization and in vitro biomedical applications of Hibiscus rosa-sinensis Linn.-mediated carbon quantum dots

Scientific Reports
In recent years, carbon quantum dots (CQDs) have garnered considerable attention as a promising material for biomedical applications because of their unique optical and biological properties.
Shweta Yalshetti, Bothe Thokchom, Santosh Mallikarjun Bhavi, Sapam Riches Singh, Sneha R. Patil, B. P. Harini, Mika Sillanpää, J. G. Manjunatha, B. S. Srinath, Ramesh Babu Yarajarla   +9 more
doaj   +1 more source

Antioxidant and anti-diabetic potential of the green synthesized silver nanoparticles using Martynia annua L. root extract

Nano TransMed
The weed Martynia annua traditionally known as Kakanasika is annual herbaceous plant known for its multiple medicinal properties such as anthelmintic, analgesic, antipyretic, antibacterial, anti-convulsant, anti-fertility, antinociceptive, antioxidant ...
Megha B. Abbigeri, Bothe Thokchom, Sapam Riches Singh, Santosh Mallikarjun Bhavi, B.P. Harini, Ramesh Babu Yarajarla   +5 more
doaj   +1 more source

Quantification of food intake in Drosophila [PDF]

, 2009
Measurement of food intake in the fruit fly Drosophila melanogaster is often necessary for studies of behaviour, nutrition and drug administration. There is no reliable and agreed method for measuring food intake of flies in undisturbed, steady state ...
Linda Partridge, Partridge, L., Wong, Richard, Matthew D. W. Piper, Partridge Linda, Richard Wong, Wong, R., Wertheim, B., Wertheim, B, Matthew D W Piper, Piper, Matthew D W, Piper, M.D.W., Partridge, Linda, Wertheim Bregje, Wong, R, Piper, MDW, Wertheim, Bregje, Piper Matthew D. W., Wertheim, Bregje; id_orcid, Partridge, L, Bregje Wertheim, Piper, M., Raine, N.E., Wong Richard   +23 more
core   +2 more sources

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

An evaluation of carbon dots derived from Amaranthus tricolor (L.) leaves for their physicochemical, photoluminescent, and biomedical properties

Discover Applied Sciences
This study explores the synthesis, characterization, and bio-functional potential of carbon dots (CDs) derived from Amaranthus tricolor (AT-CDs). Phytochemical analysis confirmed the presence of bioactive compounds while quantitative assays revealed a ...
Sapam Riches Singh, Santosh Mallikarjun Bhavi, Bothe Thokchom, Megha B. Abbigeri, Akshata Choudhari Padti, Akshata Yadawad, B. P. Harini, Chandramohan Govindasamy, Khalid M. Almutairi, Ramesh Babu Yarajarla   +9 more
doaj   +1 more source