Results 61 to 70 of about 752,872 (357)

Microwave-assisted synthesis, characterization and in vitro biomedical applications of Hibiscus rosa-sinensis Linn.-mediated carbon quantum dots

open access: yesScientific Reports
In recent years, carbon quantum dots (CQDs) have garnered considerable attention as a promising material for biomedical applications because of their unique optical and biological properties.
Shweta Yalshetti   +9 more
doaj   +1 more source

qDATA - an R application implementing a practical framework for analyzing quantitative real-time PCR data

open access: yesBioTechniques
Gene expression assays that are based on quantitative real-time PCR (qRT-PCR) method are still very popular, therefore, we developed qDATA, an open-source R-based bioinformatics application that offers a quick and intuitive analysis of raw cycle ...
Adrian Ionascu   +3 more
doaj   +1 more source

Fabrication and Evaluation of Basil Essential Oil-Loaded Halloysite Nanotubes in Chitosan Nanocomposite Film and Its Application in Food Packaging

open access: yesAntibiotics, 2022
Increasing health concerns regarding the use of plasticware have led to the development of ecofriendly biodegradable packaging film from natural polymer and food additives. In the present study, basil essential oil (BEO) loaded halloysite nanotubes (HNTs)
Narayan Chaudhary   +5 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

The Impact of Oxford Nanopore Technologies Based Methodologies on the Genome Sequencing and Assembly of Romanian Strains of Drosophila suzukii

open access: yesInsects
Background: Drosophila suzukii is a worldwide invasive species with serious economic impacts. Herein, we are presenting the first project of sequencing and assembling the whole genomes of two lines of D.
Attila Cristian Ratiu   +2 more
doaj   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

open access: yesMolecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Protective capacity of carotenoid trans-astaxanthin in rotenone-induced toxicity in Drosophila melanogaster

open access: yesScientific Reports, 2022
Trans-astaxanthin (TA), a keto-carotenoid found in aquatic invertebrates, possesses anti-oxidative and anti-inflammatory activities. Rotenone is used to induce oxidative stress-mediated Parkinson’s disease (PD) in animals.
Temitope C. Akinade   +9 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

An evaluation of carbon dots derived from Amaranthus tricolor (L.) leaves for their physicochemical, photoluminescent, and biomedical properties

open access: yesDiscover Applied Sciences
This study explores the synthesis, characterization, and bio-functional potential of carbon dots (CDs) derived from Amaranthus tricolor (AT-CDs). Phytochemical analysis confirmed the presence of bioactive compounds while quantitative assays revealed a ...
Sapam Riches Singh   +9 more
doaj   +1 more source

Eco-synthesized silver nanoparticles from Curcuma longa leaves: Phytochemical and biomedical applications

open access: yesNext Nanotechnology
Nanotechnology has revolutionized biomedical sciences, with silver nanoparticles (AgNPs) gaining attention for their antimicrobial, antioxidant, and anti-inflammatory properties. However, conventional synthesis methods often involve toxic chemicals.
Sapam Riches Singh   +9 more
doaj   +1 more source

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