Results 51 to 60 of about 913,402 (352)

Exploring the neurotoxicity and changes in life cycle parameters of Drosophila melanogaster exposed to arecoline

Journal of Basic and Applied Zoology, 2018
Background Arecoline (an alkaloid) has been reported as a potent cytotoxic as well as genotoxic agent but its neurotoxic effects are limited. Material and methods In the present study, we evaluated the neurotoxic effects and changes in life cycle ...
Barkha Shakya, Yasir Hasan Siddique
doaj   +1 more source

Identification of microtubule-associated proteins in the centrosome, spindle, and kinetochore of the early Drosophila embryo. [PDF]

, 1989
We have developed affinity chromatography methods for the isolation of microtubule-associated proteins (MAPs) from soluble cytoplasmic extracts and have used them to analyze the cytoskeleton of the early Drosophila embryo.
Alberts, BM, Field, CM, Kellogg, DR
core  

A common genetic target for environmental and heritable influences on aggressiveness in Drosophila [PDF]

, 2008
Environmental and genetic factors can modulate aggressiveness, but the biological mechanisms underlying their influence are largely unknown. Social experience with conspecifics suppresses aggressiveness in both vertebrate and invertebrate species ...
Baier, Ben-Shahar, Black, Carney, Champagne, Chen, D. J. Anderson, Dierick, Dow, Ganguly-Fitzgerald, H. Dankert, Kravitz, L. Wang, Levine, Loeber, Luciano, Manoli, Matsumoto, Matsumoto, Meerts, Osborne, P. Perona, Robinow, Soma, Stevenson, Svetec, Tecott, Toda, van der Goes van Naters, Vosshall, Wang, White, Yeager, Yeh   +33 more
core   +3 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

The Impact of Oxford Nanopore Technologies Based Methodologies on the Genome Sequencing and Assembly of Romanian Strains of Drosophila suzukii

Insects
Background: Drosophila suzukii is a worldwide invasive species with serious economic impacts. Herein, we are presenting the first project of sequencing and assembling the whole genomes of two lines of D.
Attila Cristian Ratiu, Adrian Ionascu, Nicoleta Denisa Constantin   +2 more
doaj   +1 more source

In the quest for the ideal sweetener: Aspartame exacerbates selected biomarkers in the fruit fly (Drosophila melanogaster) model of Alzheimer's disease more than sucrose

Aging Brain, 2023
This study evaluated the effect of dietary inclusions of aspartame and sucrose on some selected behavioral and biochemical indices linked with Alzheimer's disease in a transgenic fruit fly (Drosophila melanogaster) model expressing human amyloid ...
Bukola Christiana Adedayo, Stephanie Tolulope Akinniyi, Opeyemi Babatunde Ogunsuyi, Ganiyu Oboh   +3 more
doaj   +1 more source

Design and construction of a new Drosophila species, D.synthetica, by synthetic regulatory evolution [PDF]

, 2011
Here, I merge the principles of synthetic biology^1,2^ and regulatory evolution^3-11^ to create a new species^12-15^ with a minimal set of known elements.
Eduardo Moreno
core   +1 more source

A role for kinesin heavy chain in controlling vesicle transport into dendrites in Drosophila. [PDF]

, 2011
The unique architecture of neurons requires the establishment and maintenance of polarity, which relies in part on microtubule-based transport to deliver essential cargo into dendrites.
Goldstein, Lawrence SB, Henthorn, Kristina Schimmelpfeng, Herrera, Cheryl, Roux, Meike Sabina   +3 more
core   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Evidence that natural selection maintains genetic variation for sleep in Drosophila melanogaster. [PDF]

, 2015
BackgroundDrosophila melanogaster often shows correlations between latitude and phenotypic or genetic variation on different continents, which suggests local adaptation with respect to a heterogeneous environment.
Begun, David J, Chiu, Joanna C, Saelao, Perot, Svetec, Nicolas, Zhao, Li   +4 more
core   +1 more source