Results 81 to 90 of about 710,573 (349)

An assessment of the rescue action of resveratrol in parkin loss of function-induced oxidative stress in Drosophila melanogaster

Scientific Reports, 2022
Loss-of-function mutations in parkin is associated with onset of juvenile Parkinson’s disease (PD). Resveratrol is a polyphenolic stilbene with neuroprotective activity. Here, we evaluated the rescue action of resveratrol in parkin mutant D. melanogaster.
Adeola O. Adedara, Ayoade D. Babalola, Flora Stephano, Ifeoluwa O. Awogbindin, James O. Olopade, João B. T. Rocha, Alexander J. Whitworth, Amos O. Abolaji   +7 more
doaj   +1 more source

Drosophila haematopoiesis

Cellular Microbiology, 2007
Like in vertebrates, Drosophila haematopoiesis occurs in two waves. It gives rise to three types of haemocytes: plasmatocytes (phagocytosis), crystal cells (melanization) and lamellocytes (encapsulation of parasites). A first population of haemocytes, specified during embryogenesis, gives rise to an invariant number of plasmatocytes and crystal cells ...
Marie Meister, Michèle Crozatier
openaire   +3 more sources

Stereotyped Subclones Revealed by High‐Density Single‐Cell Lineage Tracing Support Robust Development

Advanced Science, EarlyView.
Based on a well‐established in vitro directed differentiation model and an integrated analysis of high‐density cell lineage trees (CLTs) and single‐cell transcriptomes, it is demonstrated that many subclones are formed by sub‐CLTs resembling each other in terms of both cell type compositions and topological structures.
Xiaoyu Zhang, Zizhang Li, Jingyu Chen, Wenjing Yang, Xingxing He, Peng Wu, Feng Chen, Ziwei Zhou, Chenze Ren, Yuyan Shan, Xiewen Wen, Vassily A. Lyubetsky, Leonid Yu. Rusin, Xiaoshu Chen, Jian‐Rong Yang   +14 more
wiley   +1 more source

Design and construction of a new Drosophila species, D.synthetica, by synthetic regulatory evolution [PDF]

, 2011
Here, I merge the principles of synthetic biology^1,2^ and regulatory evolution^3-11^ to create a new species^12-15^ with a minimal set of known elements.
Eduardo Moreno
core   +1 more source

Endocrine remodelling of the adult intestine sustains reproduction in Drosophila. [PDF]

, 2015
The production of offspring is energetically costly and relies on incompletely understood mechanisms that generate a positive energy balance. In mothers of many species, changes in key energy-associated internal organs are common yet poorly characterised
Abdou, Al-Anzi, Antonello, Athippozhy, Avila, Bajgar, Barnes, Biteau, Biteau, Bontonou, Buchon, Busson, Carey, Carvalho, Casirola, Cerf, Charles, Choi, Cognigni, David, Economos, Fahrbach, Flatt, Flatt, Flatt, Glinoer, Gore, Gwinn, Hammond, Hansen, Hildebrandt, Horton, Jiang, Jindra, Jindra, Jowett, Keller, Klepsatel, Koren, Koyama, Kubli, Kunte, Langevin, Lee, Lemaitre, Li, Lodhi, Marianes, Marois, McGuire, Micchelli, Middleton, Min, Mirth, Mirth, Moshitzky, Navare, Nijhout, O'Brien, Padmanabha, Palm, Parker, Parra-Peralbo, Phillips, Piersma, R Development Core Team, Rauschenbach, Rera, Riddiford, Roa, Rogina, Ryu, Sarraf-Zadeh, Schneider, Seegmiller, Shimano, Shin, Sieber, Siegmund, Song, Speakman, Theopold, Tiu, Ueyama, Venables, Wen, Wigby, Wyatt, Yamamoto, Yin, Zhang   +90 more
core   +2 more sources

Therapeutic evaluation of Martynia annua derived carbon dots in epileptic Drosophila model

Scientific Reports
This study investigates the synthesis and characterization of Carbon dots (MA-CDs) derived from the aqueous extract of Martynia annua and examining their potential effects in an epilepsy model Drosophila melanogaster. Phytochemical analysis confirmed the
Megha B. Abbigeri, Muskan Khan, Bothe Thokchom, Sapam Riches Singh, Santosh Mallikarjun Bhavi, Sudheendra Rao Kulkarni, B. P. Harini, G. Vidya Sagar Reddy, Chandramohan Govindasamy, Khalid M. Almutairi, Yarajarla Ramesh Babu   +10 more
doaj   +1 more source

Effect of Centella asiatica Leaf Extract on the Dietary Supplementation in Transgenic Drosophila Model of Parkinson’s Disease

Parkinson's Disease, 2014
The role of Centella asiatica L. leaf extract was studied on the transgenic Drosophila model flies expressing normal human alpha synuclein (h-αS) in the neurons. The leaf extract was prepared in acetone and was subjected to GC-MS analysis. C.
Yasir Hasan Siddique, Falaq Naz, Smita Jyoti, Ambreen Fatima, Saba Khanam, Rahul, Fahad Ali, Syed Faiz Mujtaba, Mohammad Faisal   +8 more
doaj   +1 more source

Alistipes senegalensis is Critically Involved in Gut Barrier Repair Mediated by Panax Ginseng Neutral Polysaccharides in Aged Mice

Advanced Science, EarlyView.
An integral functional axis through which GPN and functional metabolites of Alistipes senegalensis can hydrolyze tryptophan into indoles. Furthermore, the Alistipes senegalensis‐indole‐AhR pathway is found to be associated with increased expression of tight junction‐associated proteins and activation of gut stem cells.
Dandan Wang, Hui Wang, Yingna Li, Jing Lu, Xiaolei Tang, Dan Yang, Manying Wang, Daqing Zhao, Fangbing Liu, Shuai Zhang, Liwei Sun   +10 more
wiley   +1 more source

Kinesin Light Chains Are Essential for Axonal Transport in Drosophila [PDF]

, 1998
Kinesin is a heterotetramer composed of two 115-kD heavy chains and two 58-kD light chains. The microtubule motor activity of kinesin is performed by the heavy chains, but the functions of the light chains are poorly understood.
Beushausen, Sven, Desai, Chand J., Gindhart, Joseph G., Jr., Goldstein, Lawrence S. B., Zinn, Kai   +4 more
core   +2 more sources

Toxicological assessment and risk management of nanoparticles mediated composite materials-critical review: state of the art

Discover Polymers
Around the world, new composites, nanomaterial (NM) products, and tailored nanoparticles (NPs) are constantly being developed. Due to its many applications in the rapidly expanding field of nanotechnology, the manufacturing of nanoparticles is growing ...
Gaurav Pathak, Swati Mangla, Guddu Kumar Gupta, Veer Bhan, Rajeev Kumar Kapoor   +4 more
doaj   +1 more source