Results 141 to 150 of about 437,033 (326)

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy, Dávid Mező, Kinga K. Nagy, Viktória Perey‐Simon, Judit Tóth, Angéla Békési, Beáta Vértessy, Máté Varga   +7 more
wiley   +1 more source

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

Processing of insect retrotransposons by self-cleaving ribozymes [PDF]

, 2010
We show that several classes of insect non-LTR retrotransposons harbor self-cleaving ribozymes of the HDV family at their 5′ termini. In Drosophila the R2 ribozymes exhibit highly differential in vivo expression and robust in vitro activity ...
Andrej Luptak, Chiu-Ho T. Webb, Dana J. Ruminski, Nathan J. Riccitelli   +3 more
core   +1 more source

Analysis of Gene Expression in Aedes aegypti Suggests Changes in Early Genetic Control of Mosquito Development

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
ABSTRACT Aedes aegypti, a critical vector for tropical diseases, poses significant challenges for studying its embryogenesis due to difficulties in removing its rigid chorion and achieving effective fixation for in situ hybridization. Here, we present novel methodologies for fixation, dechorionation, DAPI staining, and in situ hybridization, enabling ...
Renata Coutinho‐dos‐Santos, Danielle Santos, Lupis Ribeiro, Jonathan J. Mucherino‐Muñoz, Marcelle Uhl, Carlos Logullo, A. Mendonça‐Amarante, M. Fantappie, Rodrigo Nunes‐da‐Fonseca   +8 more
wiley   +1 more source

Appraisal of species composition and ecology of Drosophilids in the Lower Swat Valley, Pakistan

International Journal of Applied and Experimental Biology
The drosophilid fauna of Pakistan remains largely understudied with numerous cities in the country yet to be thoroughly surveyed. This study aimed to investigate the drosophilid fauna of tehsil Babuzai in the Lower Swat Valley, Pakistan.
Hamid Ur Rahman, Gulalai Hadi
doaj   +1 more source

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

Individual variation in perceived density of conspecifics and its impacts on the realization of ecological niches

Oikos, EarlyView.
Animals gather information about their surroundings, including their social environment, using a wide range of sensory modalities. Variation in reception, processing and interpretation of information (cues or signals) can lead to differences in how individuals perceive their local environment. Yet, how individual differences in environmental perception
Ane Liv Berthelsen, Barbara A. Caspers, Nayden Chakarov, Alexandra K. Childs, Angelica Coculla, Melanie Dammhahn, Maria Moiron, Max Mühlenhaupt, Caroline Müller, Jules Petit, Tim M. Rapp, Nora K. E. Schulz, Svenja Stoehr, David L. J. Vendrami   +13 more
wiley   +1 more source

Rate and cost of adaptation in the Drosophila Genome

, 2014
Recent studies have consistently inferred high rates of adaptive molecular evolution between Drosophila species. At the same time, the Drosophila genome evolves under different rates of recombination, which results in partial genetic linkage between ...
Lässig, Michael, Mustonen, Ville, Schiffels, Stephan   +2 more
core   +1 more source

The genome sequence of Drosophila melanogaster.

Science, 2000
M. Adams, S. Celniker, R. Holt, C. Evans, J. Gocayne, P. Amanatides, S. Scherer, P. Li, R. Hoskins, R. Galle, R. George, S. Lewis, S. Richards, M. Ashburner, S. Henderson, G. Sutton, J. Wortman, M. Yandell, Q. Zhang, L. Chen, R. Brandon, Y. Rogers, R. Blazej, M. Champe, B. Pfeiffer, K. Wan, C. Doyle, E. G. Baxter, G. Helt, C. Nelson, G. Gábor, J. F. Abril, A. Agbayani, H. An, C. Andrews-Pfannkoch, D. Baldwin, R. Ballew, A. Basu, J. Baxendale, L. Bayraktaroglu, E. Beasley, K. Beeson, P. Benos, B. Berman, D. Bhandari, S. Bolshakov, D. Borkova, M. Botchan, J. Bouck, P. Brokstein, P. Brottier, K. C. Burtis, D. Busam, H. Butler, É. Cadieu, A. Center, I. Chandra, J. Cherry, S. Cawley, C. Dahlke, L. Davenport, P. Davies, B. de Pablos, A. Delcher, Z. Deng, A. Mays, I. Dew, S. Dietz, K. Dodson, L. Doup, M. Downes, S. Dugan-Rocha, B. Dunkov, P. Dunn, K. Durbin, C. Evangelista, C. Ferraz, S. Ferriera, W. Fleischmann, C. Fosler, A. Gabrielian, N. Garg, W. Gelbart, K. Glasser, A. Glodek, F. Gong, J. H. Gorrell, Z. Gu, P. Guan, M. Harris, N. Harris, D. Harvey, T. J. Heiman, J. Hernandez, J. Houck, D. Hostin, K. Houston, T. Howland, M. Wei, C. Ibegwam, M. Jalali, F. Kalush, G. Karpen, Z. Ke, J. Kennison, K. Ketchum, B. E. Kimmel, C. Kodira, C. Kraft, S. Kravitz, D. Kulp, Z. Lai, P. Lasko, Y. Lei, A. Levitsky, J. Li, Z. Li, Y. Liang, X. Lin, X. Liu, B. Mattei, T. McIntosh, M. P. McLeod, D. McPherson, G. Merkulov, N. Milshina, C. Mobarry, J. Morris, A. Moshrefi, Stephen M. Mount, M. Moy, B. Murphy, L. Murphy, D. Muzny, D. Nelson, D. Nelson, K. Nelson, K. Nixon, D. Nusskern, J. Pacleb, M. Palazzolo, G. Pittman, S. Pan, J. Pollard, V. Puri, M. G. Reese, K. Reinert, K. Remington, R. Saunders, F. Scheeler, H. Shen, B. Shue, I. Sidén-Kiamos, M. Simpson, M. Skupski, T. Smith, E. Spier, A. Spradling, M. Stapleton, R. Strong, E. Sun, Rob Svirskas, C. Tector, R. Turner, E. Venter, A. H. Wang, X. Wang, Z. Y. Wang, D. Wassarman, G. Weinstock, J. Weissenbach, S. Williams, WoodageT, K. Worley, D. Wu, S. Yang, Q. Yao, J. Ye, R. Yeh, J. Zaveri, M. Zhan, G. Zhang, Q. Zhao, L. Zheng, X. H. Zheng, F. Zhong, W. Zhong, X. Zhou, S. Zhu, X. Zhu, H. Smith, R. Gibbs, E. Myers, G. Rubin, J. Venter   +194 more
semanticscholar   +1 more source

RNA degradomics and proteomics reveal the mechanism of dsProsβ1‐mediated proteasome targeting in Psylliodes chrysocephala

Pest Management Science, EarlyView.
RNA degradomics revealed dsProsβ1‐derived siRNA‐mediated mRNA cleavage events, mainly at uracil‐guanine and adenine‐adenine pairs. Proteasome inhibition via dsProsβ1 increased mitochondrial and cytoskeletal proteins while reducing translation‐related and mRNA‐binding proteins.
Doga Cedden, Gözde Güney, Michael Rostás, Stefan Scholten   +3 more
wiley   +1 more source