Results 91 to 100 of about 5,958,148 (313)
Advanced Science, EarlyView.METTL1 and its mediated m7G tRNA modification are significantly up‐regulated after partial hepatectomy (PHx). Overexpression of METTL1 improves the efficiency of liver regeneration after PHx, increases the proliferation of hepatocytes, and accelerates the recovery of liver function.
Manling Huang +18 more
wiley +1 more source
Regulation of actin-Spectrin cytoskeleton by ICA69 at the Drosophila neuromuscular junction
Communicative & Integrative Biology, 2018 Bin-Amphiphysin-Rvs (BAR) domain containing proteins with their membrane deforming properties have emerged as key players in shaping up neuronal morphology and regulating cytoskeletal dynamics.
Bhagaban Mallik, Vimlesh Kumar
doaj +1 more source
Evidence of dietary protein restriction regulating pupation height, development time and lifespan in Drosophila melanogaster [PDF]
, 2019 Sudhakar Krittika +2 more
openalex +1 more source
The Drosophila blood–brain barrier regulates sleep via Moody G protein-coupled receptor signaling [PDF]
, 2023 Sofia Axelrod +11 more
openalex +1 more source
Advanced Science, EarlyView.CDGSH iron sulfur domain 1 (CISD1) mitigates oxidative stress by promoting NADH oxidation and Coenzyme Q (CoQ) reduction. Under chronic stress, elevated CISD1 expression in microglia enhances NAD⁺ production, thereby increasing GAPDH activity and glycolytic flux, while reducing ATP synthesis by inhibiting proton transfer from mitochondrial complexes I ...
Wanting Dong +5 more
wiley +1 more source
G3: Genes, Genomes, Genetics, 2018 Septin proteins are polymerizing GTPases that are found in most eukaryotic species. Septins are important for cytokinesis and participate in many processes involving spatial modifications of the cell cortex. In Drosophila, septin proteins Pnut, Sep1, and
Katarina Akhmetova +5 more
doaj +1 more source
The Drosophila RNA‐binding protein Lark is required for the organization of the actin cytoskeleton and Hu‐li tai shao localization during oogenesis [PDF]
, 2004 Gerard P. McNeil +2 more
openalex +1 more source
Stabilized Ion Selectivity Corrects Activation Drift in Kalium Channelrhodopsins
Advanced Science, EarlyView.As newly emerged optogenetic tools, potassium channelrhodopsins (KCRs) can drift from inhibition to activation during illumination as K⁺ selectivity declines. It is shown that both the absolute K⁺/Na⁺ permeability ratio and its stability over time govern this drift, identify KCR1‐C29D as a reliably inhibitory variant, and outline design principles for ...
Xiao Duan +14 more
wiley +1 more source
Advanced Science, EarlyView.Seasonal cold adaptation is vital for insect survival, yet the molecular mechanisms linking diapause to mitochondrial resilience remain largely unresolved. We identify ascaroside C9 (asc‐C9) as a key endocrine signal that enhances diapause survival during cold stress by activating the AKHR–PGC1α–UCP4 axis, thereby driving cold‐induced lipolysis and ...
Jiao Zhou +14 more
wiley +1 more source
Geometrically Encoded Positioning of Introns, Intergenic Segments, and Exons in the Human Genome
Advanced Science, EarlyView.This study introduces a new hypothesis: exons, introns, and intergenic segments are non‐random projections of the functional layers of 3D structure of chromatin packing domains. Evidence is presented that this “geometric code” may encode volumetric structure, reconciling epigenetic patterns, correlates with oncogenic mutations, acting as a potential ...
Luay M. Almassalha +11 more
wiley +1 more source