Results 91 to 100 of about 5,995,584 (403)

Proteomics Reveals Novel Drosophila Seminal Fluid Proteins Transferred at Mating

open access: yesPLoS Biology, 2008
Across diverse taxa, seminal fluid proteins (Sfps) transferred at mating affect the reproductive success of both sexes. Such reproductive proteins often evolve under positive selection between species; because of this rapid divergence, Sfps are ...
Geoffrey D. Findlay   +3 more
semanticscholar   +1 more source

DNA‐PKcs‐Driven YAP1 Phosphorylation and Nuclear Translocation: a Key Regulator of Ferroptosis in Hyperglycemia‐Induced Cardiac Dysfunction in Type 1 Diabetes

open access: yesAdvanced Science, EarlyView.
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang   +10 more
wiley   +1 more source

The Roles of the LIM Domain Proteins in Drosophila Cardiac and Hematopoietic Morphogenesis

open access: yesFrontiers in Cardiovascular Medicine, 2021
Drosophila melanogaster has been used as a model organism for study on development and pathophysiology of the heart. LIM domain proteins act as adaptors or scaffolds to promote the assembly of multimeric protein complexes. We found a total of 75 proteins
Meihua She   +3 more
doaj   +1 more source

Neurofly 2008 abstracts : the 12th European Drosophila neurobiology conference 6-10 September 2008 Wuerzburg, Germany [PDF]

open access: yes, 2009
This volume consists of a collection of conference ...
Buchner, Erich, Heisenberg, Martin
core  

The selectivity and specificity of autophagy in drosophila [PDF]

open access: yes, 2012
Autophagy is a process of cellular self-degradation and is a major pathway for elimination of cytoplasmic material by the lysosomes. Autophagy is responsible for the degradation of damaged organelles and protein aggregates and therefore plays a ...
Chou   +27 more
core   +2 more sources

A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins.

open access: yesGenes & Development, 2002
Fragile X syndrome is a common form of inherited mental retardation caused by the loss of FMR1 expression. The FMR1 gene encodes an RNA-binding protein that associates with translating ribosomes and acts as a negative translational regulator.
A. Ishizuka, M. Siomi, H. Siomi
semanticscholar   +1 more source

Genetics‐Based Targeting Strategies for Precise Neuromodulation

open access: yesAdvanced Science, EarlyView.
In this Review, the fundamental principles and implementation protocols of genetics‐based precision neuromodulation are first introduced. Then, wireless and low‐invasive strategies based on nano‐transducing materials are highlighted, along with a dissection and analysis of the strengths and weaknesses of representative studies.
Yuyuan He   +11 more
wiley   +1 more source

A mighty small heart: the cardiac proteome of adult Drosophila melanogaster.

open access: yesPLoS ONE, 2011
Drosophila melanogaster is emerging as a powerful model system for the study of cardiac disease. Establishing peptide and protein maps of the Drosophila heart is central to implementation of protein network studies that will allow us to assess the ...
Anthony Cammarato   +13 more
doaj   +1 more source

piRNAs and Aubergine cooperate with Wispy poly(A) polymerase to stabilize mRNAs in the germ plasm [PDF]

open access: yes, 2017
Piwi-interacting RNAs (piRNAs) and PIWI proteins play a crucial role in germ cells by repressing transposable elements and regulating gene expression. In Drosophila, maternal piRNAs are loaded into the embryo mostly bound to the PIWI protein Aubergine ...
Beilharz, Traude H.   +9 more
core   +3 more sources

Alistipes senegalensis is Critically Involved in Gut Barrier Repair Mediated by Panax Ginseng Neutral Polysaccharides in Aged Mice

open access: yesAdvanced Science, EarlyView.
An integral functional axis through which GPN and functional metabolites of Alistipes senegalensis can hydrolyze tryptophan into indoles. Furthermore, the Alistipes senegalensis‐indole‐AhR pathway is found to be associated with increased expression of tight junction‐associated proteins and activation of gut stem cells.
Dandan Wang   +10 more
wiley   +1 more source

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