Results 171 to 180 of about 5,958,148 (313)
Protocol for Reconstituting Adaptor‐Mediated Activation of Full‐Length Kinesin‐1
ABSTRACT Kinesin‐1 is a member of the kinesin superfamily that plays an essential role in intracellular cargo transport. In the absence of cargo, Kinesin‐1 exhibits low motor activity due to autoinhibition. Multiple studies have demonstrated that adaptor proteins, which link cargos to Kinesin‐1, can activate Kinesin‐1 by releasing the autoinhibition ...
Haruka Masumoto, Kyoko Chiba
wiley +1 more source
Loss of Drosophila <i>UBE3A</i> phenocopies Piezo dysfunction and drives hyperphagic feeding in Drosophila. [PDF]
Geier B, Neely L, Coronado E, Reiter LT.
europepmc +1 more source
Antioxidant proteins TSA and PAG interact synergistically with Presenilin to modulate Notch signaling in Drosophila [PDF]
Michael F. Wangler +5 more
openalex +1 more source
ABSTRACT Cooperativity between cytoskeletal proteins is crucial for spatiotemporal coordination in biological processes, like oogenesis. In mammalian and Drosophila oogenesis, proper assembly and function of actin networks require coordination between actin assembly factors Spire and formins, as well as actin‐associated proteins like myosins and Rab ...
Joseph Y. Ong +7 more
wiley +1 more source
Genetic Modeling of Lysosomal Storage Disorders (LSDs) in the Brain-Midgut Axis of <i>Drosophila melanogaster</i> During Aging. [PDF]
Markaki SP +5 more
europepmc +1 more source
Mitochondria and the Actin Cytoskeleton in Neurodegeneration
ABSTRACT Mitochondrial dysfunction and cytoskeletal disorganization are widely recognized hallmarks of neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS).
Shivani Tuli +3 more
wiley +1 more source
Mitochondrial genome dataset of <i>Drosophila melanogaster</i> Meigen, 1830 (fruit fly) from Pakistan. [PDF]
Arshad S +3 more
europepmc +1 more source

