Results 311 to 320 of about 387,028 (358)

Adaptive protein evolution in Drosophila

Nature, 2002
For over 30 years a central question in molecular evolution has been whether natural selection plays a substantial role in evolution at the DNA sequence level. Evidence has accumulated over the last decade that adaptive evolution does occur at the protein level, but it has remained unclear how prevalent adaptive evolution is.
Nick G C, Smith, Adam, Eyre-Walker
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Synthesis of drosophila X virus proteins in cultured Drosophila cells

Virology, 1984
The genome of Drosophila X virus (DXV) is made up of two segments of dsRNA with molecular weights of 2.3 X 10(6) (A) and 2.2 X 10(6) (B). Agarose gel electrophoresis of RNA fragments produced by S1 nuclease digestion of partially denatured, purified segment A and B indicated that the two genome segments have different nucleotide sequences.
E, Nagy, P, Dobos
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Drosophila RNA Binding Proteins

2006
RNA binding proteins are fundamental mediators of gene expression. The use of the model organism Drosophila has helped to elucidate both tissue-specific and ubiquitous functions of RNA binding proteins. These proteins mediate all aspects of the mRNA lifespan including splicing, nucleocytoplasmic transport, localization, stability, translation, and ...
Chiara, Gamberi, Oona, Johnstone, Paul, Lasko   +2 more
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Protein Expression in Drosophila Schneider Cells

Analytical Biochemistry, 2000
We expressed recombinant secreted, membrane, and cytosolic proteins in stably transfected Drosophila Schneider (SL-3) cells. To allow easy cloning of N- and C-terminal fusion proteins containing epitope- and His-tags for the detection of recombinant proteins and purification by affinity chromatography we constructed new expression vectors. To exemplify
J, Benting, S, Lecat, D, Zacchetti, K, Simons   +3 more
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Drosophila protein tyrosine phosphatases

Seminars in Cell Biology, 1993
Seven protein tyrosine phosphatase (PTPase) genes have been identified in the fruit-fly Drosophila melanogaster. Four of these genes encode receptor-linked PTPases (R-PTPs) that are expressed on central nervous system axons in the embryo. Each axonal R-PTP has an extracellular domain that is homologous to vertebrate adhesion molecules and to identified
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Wolffish Antifreeze Protein from Transgenic Drosophila

Nature Biotechnology, 1990
We have expressed two antifreeze protein genes from the Atlantic wolffish, Anarhichas lupus, in Drosophila melanogaster by placing them under the divergent transcriptional control of the host yolk polypeptide (1 and 2) gene promoters. Both genes were joined to the central promoter region by fusion within the DNA encoding the signal polypeptides.
D E, Rancourt, I D, Peters, V K, Walker, P L, Davies   +3 more
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Protein and enzyme variation in Drosophila

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1971
Abstract 1. 1. The isoenzyme patterns of alcohol dehydrogenase (ADH), glutamate dehydrogenase (GDH), and lactate dehydrogenase (LDH), and the protein banding patterns of Drosophila affinis, D. hydei, D. melanogaster, D. simulans Amherst, D. simulans Georgetown, and D.
P W, Pappas, G E, Rodrick, J R, Diebolt
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Peroxisome Protein Prediction in Drosophila melanogaster

2018
As a laboratory animal, Drosophila melanogaster has made extensive contributions to understanding many areas of fundamental biology as well as being an effective model for human disease. Until recently, there was relatively little known about fly peroxisomes.
Matthew, Anderson-Baron, Andrew J, Simmonds   +1 more
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Drosophila melanogaster larval hemolymph protein mapping

Biochemical and Biophysical Research Communications, 2003
With the completion of the genome sequence of Drosophila melanogaster the importance of constructing a proteome map is to be considered. Therefore, with the application of recent advances in proteomic analysis approaches, a protein map of D. melanogaster larvae hemolymph proteins was obtained using 2-DE in the range of pH 3-10.
Sofia de Morais, Guedes, Rui, Vitorino, Kenneth, Tomer, M Rosário M, Domingues, A J Ferrer, Correia, Francisco, Amado, Pedro, Domingues   +6 more
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Serine/threonine protein kinases in Drosophila

Trends in Genetics, 1990
The study of serine/threonine kinases in Drosophila is coming of age. Recently several kinases have been identified and their role in cell determination has been established. This review discusses these recent findings and describes the potential for genetic analyses of kinase activity and signal transduction.
E, Siegfried, L, Ambrosio, N, Perrimon
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