Results 1 to 10 of about 1,364 (160)

Belly dancer syndrome improved by withdrawal of droxidopa and amantadine. [PDF]

open access: goldClin Case Rep, 2023
A man hospitalized for cerebral infarction developed drug‐induced belly dancer syndrome, which improved after withdrawal of droxidopa and amantadine. Drugs that modulate dopamine neurotransmission have been reported to be associated with this syndrome ...
Kaga M   +6 more
europepmc   +7 more sources

Multitargeted docking approach reveals droxidopa against DNA replication and repair-related protein of cervical cancer. [PDF]

open access: goldSci Rep
Cervical cancer begins in the cells lining the cervix and is caused by persistent infection with certain types of human papillomavirus (HPV). Initially, it has no symptoms, and later it causes pelvic pain, abnormal vaginal bleeding, and pain during ...
Alsaiari AA   +9 more
europepmc   +4 more sources

Use of droxidopa for blood pressure augmentation after acute spinal cord injury: case reports. [PDF]

open access: diamondAcute Crit Care, 2022
Hypotension secondary to autonomic dysfunction is a common complication of acute spinal cord injury (SCI) that may worsen neurologic outcomes. Midodrine, an enteral α-1 agonist, is often used to facilitate weaning intravenous (IV) vasopressors, but its ...
Hong CS   +11 more
europepmc   +5 more sources

Ampreloxetine Versus Droxidopa in Neurogenic Orthostatic Hypotension: A Comparative Review. [PDF]

open access: diamondCureus, 2023
Neurogenic orthostatic hypotension (nOH) is a disabling problem of autonomic dysfunction in patients with Parkinson’s disease, which is associated with poor quality of life and higher mortality rates.
Hoxhaj P   +12 more
europepmc   +4 more sources

Droxidopa as an effective treatment for refractory neurogenic orthostatic hypotension and reflex bradycardia in amyloid light-chain amyloidosis: a case report [PDF]

open access: goldJournal of Medical Case Reports, 2020
Background Droxidopa is an oral treatment for the stepwise treatment of neurogenic orthostatic hypotension from autonomic dysfunction. It has been shown to be useful predominantly with neurogenic orthostatic hypotension secondary to Parkinson’s disease ...
Annie H. Ho   +4 more
semanticscholar   +4 more sources

Psychometric validation of a patient-reported single-item assessment of ‘Good Day Bad Day’ in a neurogenic orthostatic hypotension population treated with droxidopa

open access: goldJournal of Market Access & Health Policy, 2022
Background Symptoms of neurogenic orthostatic hypotension (nOH), including lightheadedness/dizziness, presyncope, syncope, and falls, can lead to impaired functional ability and reduced quality of life.
C. François   +5 more
semanticscholar   +3 more sources

L-DOPA and Droxidopa: From Force Field Development to Molecular Docking into Human β2-Adrenergic Receptor. [PDF]

open access: yesLife (Basel), 2022
The increasing interest in the molecular mechanism of the binding of different agonists and antagonists to β2-adrenergic receptor (β2AR) inactive and active states has led us to investigate protein–ligand interactions using molecular docking calculations.
Catte A, Biswas AD, Mancini G, Barone V.
europepmc   +4 more sources

Durability of the Clinical Benefit of Droxidopa for Neurogenic Orthostatic Hypotension During 12 Weeks of Open-Label Treatment [PDF]

open access: goldNeurological Therapeutics, 2022
Introduction Droxidopa is approved to treat neurogenic orthostatic hypotension (nOH) symptoms in patients with autonomic failure based on short-term clinical trial data. Additional data on the long-term efficacy of droxidopa are needed. We have evaluated
R. Hauser   +6 more
semanticscholar   +2 more sources

Copper oxide, ionic liquid and Mn(III) Salen modified carbon paste electrode as selective electrochemical sensor for determination of droxidopa in the presence of carbidopa [PDF]

open access: diamond, 2020
A novel electrochemical sensor for the selective and sensitive detection of droxidopa in presence of carbidopa at physiological pH was developed by the bulk modification of carbon paste electrode (CPE) with copper oxide (CuO), ionic liquid and Mn (III ...
Mohammad Reza Aflatoonian   +5 more
semanticscholar   +2 more sources

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