Neurogenic orthostatic hypotension – management update and role of droxidopa
Therapeutics and Clinical Risk Management, 2015 Joy Vijayan,1 Vijay K Sharma1,21Department of Medicine, Division of Neurology, National University Health System, 2Yong Loo Lin School of Medicine, National University of Singapore, SingaporeAbstract: Orthostatic hypotension (OH) is defined as a ...
Vijayan J, Sharma VK
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Clinical presentation and long-term follow-up of dopamine beta hydroxylase deficiency [PDF]
, 2020 Dopamine beta hydroxylase (DBH) deficiency is an extremely rare autosomal recessive disorder with severe orthostatic hypotension, that can be treated with L-threo-3,4-dihydroxyphenylserine (L-DOPS).
Deinum, Jaap +13 more
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Treatment of Nonmotor Symptoms in Parkinson's Disease [PDF]
, 2017 Nonmotor symptoms (NMS) are integral to Parkinson's disease (PD) and the management can often be challenging. In spite of the growing evidence that NMS have a key impact on the quality of life of patients and caregivers, most clinical trials still focus ...
A. Sauerbier +5 more
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Fibromyalgia pathogenesis provides drug target clues [PDF]
, 2016 Fibromyalgia (FM) has been described as a condition of heightened generalised sensitisation to sensory input presenting as a complex of symptoms dominated by chronic widespread pain characterised by hyperalgesia and allodynia. A range of co-morbidities
Lawson, Kim
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A Stage-Based Approach to Therapy in Parkinson’s Disease [PDF]
, 2019 Parkinson's disease (PD) is a neurodegenerative disorder that features progressive, disabling motor symptoms, such as bradykinesia, rigidity, and resting tremor.
Barbone, Filomena +12 more
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A Path Difficult to Tread: Pure Autonomic Failure, A Case Report [PDF]
, 2023 Introduction - Pure autonomic failure is a rare disorder characterized by orthostatic hypotension, absence of a compensatory rise in heart rate, and abnormal autonomic functions.
Dalbah, Rami +5 more
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Diagnosing and managing diabetic somatic and autonomic neuropathy [PDF]
, 2019 The diagnosis and management of diabetic neuropathy can be a major challenge. Late diagnosis contributes to significant morbidity in the form of painful diabetic neuropathy, foot ulceration, amputation, and increased mortality.
Al-Mohamedi, Abdulrahman +13 more
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Vascular Health and Risk Management, 2014 Stuart H Isaacson, Julia Skettini Parkinson's Disease and Movement Disorders Center of Boca Raton, Boca Raton, FL, USA Abstract: Neurogenic orthostatic hypotension (nOH) is due to failure of the autonomic nervous system to regulate blood pressure in
Isaacson SH, Skettini J
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Impact Of Fdaaa On Registration, Results Reporting, And Publication Of Clinical Trials Evaluating New Neuropsychiatric Drugs Approved Between 2005 And 2014 [PDF]
, 2019 Evidence-based medicine (EBM) promotes the use of randomized controlled trials (RCTs) published in peer reviewed medical journals as the “gold standard”.
Zou, Constance Xuanyi
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Recent Advances and Future Directions in Syncope Management: A Comprehensive Narrative Review [PDF]
Syncope is a highly prevalent clinical condition characterized by a rapid, complete, and brief loss of consciousness, followed by full recovery caused by cerebral hypoperfusion.
Cacciatore, Stefano +6 more
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