Results 71 to 80 of about 1,420 (176)
Neurogenic orthostatic hypotension – management update and role of droxidopa
Therapeutics and Clinical Risk Management, 2015 Joy Vijayan,1 Vijay K Sharma1,21Department of Medicine, Division of Neurology, National University Health System, 2Yong Loo Lin School of Medicine, National University of Singapore, SingaporeAbstract: Orthostatic hypotension (OH) is defined as a ...
Vijayan J, Sharma VK
doaj
Istradefylline/L‐DOPA Parkinson's disease therapy and energy coupling
Neurology and Clinical Neuroscience, Volume 12, Issue 5, Page 296-305, September 2024.Abstract Background Both dopamine and adenosine are physiologically involved in cellular energy metabolism. Aim Novel approaches targeting delaying progression strategies for Parkinson's disease (PD) examined the effects of long‐term use of A2AR antagonist/istradefylline (IST) adjunct to L‐DOPA (LD), nutshell IST‐LD, with an expected energy coupling ...
Naomi Kanzato +2 more
wiley +1 more source
A Path Difficult to Tread: Pure Autonomic Failure, A Case Report [PDF]
, 2023 Introduction - Pure autonomic failure is a rare disorder characterized by orthostatic hypotension, absence of a compensatory rise in heart rate, and abnormal autonomic functions.
Dalbah, Rami +5 more
core +1 more source
Therapeutic Apheresis and Dialysis, Volume 28, Issue 4, Page 547-556, August 2024.Abstract Introduction This study aimed to examine the associations of vitamin D receptor activators (VDRA) and calcimimetics use with falls. Methods This is a prospective cohort study on hemodialysis patients in the Japan Dialysis Outcomes and Practice Patterns Study. We excluded those who were unable to walk.
Miho Murashima +6 more
wiley +1 more source
Diagnosis and treatment of autonomic failure, pain and sleep disturbances in Parkinson’s disease: guideline “Parkinson’s disease” of the German Society of Neurology [PDF]
Background and objective Non-motor symptoms frequently develop throughout the disease course of Parkinson’s disease (PD), and pose affected individuals at risk of complications, more rapid disease progression and poorer quality of life.
Becktepe, Jos +11 more
core +1 more source
Efficacy and Safety of Elobixibat in Parkinson's Disease with Chronic Constipation: CONST‐PD Study
Movement Disorders Clinical Practice, Volume 11, Issue 4, Page 352-362, April 2024.Abstract Background Chronic constipation is a common digestive complication of Parkinson's disease (PD). Objectives To verify the usefulness of elobixibat, an ileal bile acid transporter inhibitor, for chronic constipation in PD. Methods This double‐blind, placebo‐controlled study consisted of a 2‐week observation/washout period and a 4‐week treatment ...
Taku Hatano +30 more
wiley +1 more source
Muscle &Nerve, Volume 69, Issue 3, Page 273-287, March 2024.Abstract Hereditary transthyretin (ATTRv; v for variant) amyloidosis is a rare, multisystem, progressive, and fatal disease in which polyneuropathy is a cardinal manifestation. Due to a lack of United States (US)‐specific guidance on ATTRv amyloidosis with polyneuropathy, a panel of US‐based expert clinicians convened to address identification ...
Chafic Karam +6 more
wiley +1 more source
Neurogenic orthostatic hypotension – management update and role of droxidopa
Therapeutics and Clinical Risk Management, 2015 Orthostatic hypotension (OH) is defined as a significant decrease in blood pressure (BP) during the first 3 minutes of standing or a head up on a tilt table. Symptoms of OH are highly variable, ranging from mild light-headedness to recurrent syncope.
Vijayan, Joy, Sharma, Vijay K
openaire +3 more sources
Potential Utility of 123I-MIBG Scintigraphy as a Predictor of Falls in Parkinson's Disease [PDF]
, 2019 Background: Falls are associated with poor prognosis in patients with Parkinson's disease (PD). Although several factors related to falls were reported in patients with PD, objective predictors of falls are not identified.
00214304 +43 more
core
A Stage-Based Approach to Therapy in Parkinson’s Disease [PDF]
, 2019 Parkinson's disease (PD) is a neurodegenerative disorder that features progressive, disabling motor symptoms, such as bradykinesia, rigidity, and resting tremor.
Barbone, Filomena +12 more
core +1 more source