Neurogenic Orthostatic Hypotension: a Common Complication of Successful Pancreas Transplantation [PDF]
Transplantation Direct, 2021 Background. Orthostatic hypotension (OH) is a poorly understood complication of simultaneous pancreas–kidney (SPK) transplantation. We sought to determine the incidence, timing, and relationship of OH to rapid glycemic control in the early posttransplant
Samantha A. Kuten, PharmD +9 more
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Neurogenic Orthostatic Hypotension: State of the Art and Therapeutic Strategies [PDF]
Clinical Medicine Insights: Cardiology, 2020 Neurogenic orthostatic hypotension (nOH) is a subtype of orthostatic hypotension in which patients have impaired regulation of standing blood pressure due to autonomic dysfunction. Several primary and secondary causes of this disease exist.
Dinesh K Kalra, Anvi Raina, Sumit Sohal
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Reduction in Pulse Pressure during Standing Can Distinguish Neurogenic Orthostatic Hypotension [PDF]
Diagnostics, 2021 Background: We investigated whether changes in the pulse pressure (PP) reduction ratio during the head-up tilt test (HUTT) can aid in distinguishing neurogenic orthostatic hypotension (OH) from non-neurogenic OH. Methods: We enrolled consecutive patients
Kyu-On Jung +3 more
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Genetics of Neurogenic Orthostatic Hypotension in Parkinson’s Disease, Results from a Cross-Sectional In Silico Study [PDF]
Brain Sciences, 2023 The genetic basis of Neurogenic Orthostatic Hypotension (NOH) in Parkinson’s disease (PD) has been inadequately explored. In a cross-sectional study, we examined the association between NOH and PD-related single-nucleotide polymorphisms (SNPs) and mapped
Guenson Chevalier +7 more
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Efficacy of atomoxetine versus midodrine for neurogenic orthostatic hypotension [PDF]
Annals of Clinical and Translational Neurology, 2020 Objective The efficacy and safety of 1‐month atomoxetine and midodrine therapies were compared. Three‐month atomoxetine and combination therapies were investigated for additional benefits.
Jung‐Ick Byun +13 more
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Droxidopa Persistence in Neurogenic Orthostatic Hypotension May Be Affected by Titration Approach [PDF]
International Journal of General Medicine, 2021 Fahd Amjad,1 Brett Polenchar,2 Antonella Favit3 1Department of Neurology, Georgetown University Hospital Pasquerilla Healthcare Center, Washington, DC, USA; 2Business Insights, Lundbeck, Deerfield, IL, USA; 3Medical Affairs, Lundbeck, Deerfield, IL ...
Amjad F, Polenchar B, Favit A
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Neurogenic Orthostatic Hypotension in Parkinson Disease: A Primer [PDF]
Neurology and Therapy, 2019 Abstract Parkinson disease (PD) is associated with a variety of motor and non-motor clinical manifestations, including cardiovascular autonomic dysfunction. Neurogenic orthostatic hypotension (nOH) is a potentially serious manifestation of cardiovascular
Jeremy K. Cutsforth-Gregory +1 more
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Association of neurogenic orthostatic hypotension with cognitive decline in Parkinson’s disease: a longitudinal cohort study [PDF]
Frontiers in NeurologyIntroductionNeurogenic orthostatic hypotension (nOH), a common non-motor feature of Parkinson’s disease (PD), is defined as a sustained drop in blood pressure (BP) upon standing due to autonomic dysfunction.
Neda Bagheri +2 more
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A Call to Action: The Role of Healthcare Providers in Reducing the Burden Associated with Neurogenic Orthostatic Hypotension [PDF]
Neurology and Therapy, 2020 Plain Language Summary This article discusses what neurogenic orthostatic hypotension (nOH) is, its symptoms, and how patients and healthcare providers (HCPs) can work together to manage nOH symptoms. What is nOH?
Jessie S. Gibson +2 more
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The effects of caffeine in adults with neurogenic orthostatic hypotension: a systematic review [PDF]
Clinical Autonomic Research, 2021 James Frith, Jake Ryan Gibbon
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