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Neurogenic Orthostatic Hypotension in Parkinson Disease: A Primer [PDF]

Neurology and Therapy, 2019
Abstract Parkinson disease (PD) is associated with a variety of motor and non-motor clinical manifestations, including cardiovascular autonomic dysfunction. Neurogenic orthostatic hypotension (nOH) is a potentially serious manifestation of cardiovascular
Jeremy K. Cutsforth-Gregory, Phillip A. Low   +1 more
doaj   +3 more sources

Clinical management of neurogenic orthostatic hypotension

Annals of Movement Disorders, 2019
Neurogenic orthostatic hypotension is a common disorder often seen in elderly patients affected with neurodegenerative disorders and peripheral neuropathies.
Malligurki Raghurama Rukmani, Ravi Yadav, Pramod K Pal, Talakad N Sathyaprabha   +3 more
doaj   +2 more sources

Primary neurogenic orthostatic hypotension [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 1970
Eight further cases of neurogenic orthostatic hypotension are described together with a necropsy study on one case. Three cases showed evidence of autonomic dysfunction in isolation, while in five cases this was accompanied by evidence of more diffuse central nervous system degeneration.
R C, Hughes, N E, Cartlidge, P, Millac
openaire   +2 more sources

Orthostatic hypotension: An overlooked but clinically decisive entity

Journal of the Indian Academy of Geriatrics, 2022
Orthostatic hypotension (OH) is defined as a drop of >20 mm Hg of systolic or >10 mm Hg of diastolic blood pressure (BP) within 3 min of standing from lying position. It is a common geriatric syndrome caused by impaired orthostatic response of BP.
Gunja Jain, Sunny Singhal, Laxmi Kant Goyal, Ajay Mathur   +3 more
doaj   +1 more source

Neurogenic Orthostatic Hypotension [PDF]

Circulation, 2009
Orthostatic hypotension (OH) is defined as a persistent, consistent, orthostatic fall in systolic blood pressure of ≥20 mm Hg or diastolic pressure of ≥10 mm Hg by 3 minutes of standing up.1 Acute, unexpected, episodic falls in blood pressure while standing, as in neurocardiogenic syncope, do not satisfy criteria for OH.
David S, Goldstein, Yehonatan, Sharabi
openaire   +2 more sources

Droxidopa as an effective treatment for refractory neurogenic orthostatic hypotension and reflex bradycardia in amyloid light-chain amyloidosis: a case report

Journal of Medical Case Reports, 2020
Background Droxidopa is an oral treatment for the stepwise treatment of neurogenic orthostatic hypotension from autonomic dysfunction. It has been shown to be useful predominantly with neurogenic orthostatic hypotension secondary to Parkinson’s disease ...
Annie H. Ho, Christopher W. Kinter, John Wight, Anudeep R. Neelam, David Krakow   +4 more
doaj   +1 more source

Droxidopa in neurogenic orthostatic hypotension [PDF]

Expert Review of Cardiovascular Therapy, 2015
Neurogenic orthostatic hypotension (nOH) is a fall in blood pressure (BP) on standing due to reduced norepinephrine release from sympathetic nerve terminals. nOH is a feature of several neurological disorders that affect the autonomic nervous system, most notably Parkinson disease (PD), multiple system atrophy (MSA), pure autonomic failure (PAF), and ...
Horacio, Kaufmann, Lucy, Norcliffe-Kaufmann, Jose-Alberto, Palma   +2 more
openaire   +2 more sources

Orthostatic hypotension and novel blood pressure-associated gene variants: Genetics of Postural Hemodynamics (GPH) Consortium [PDF]

, 2012
Aims: Orthostatic hypotension (OH), an independent predictor of mortality and cardiovascular events, strongly correlates with hypertension. Recent genome-wide studies have identified new loci influencing blood pressure (BP) in populations, but their ...
Almgren, Peter,, Boerwinkle, Eric, Brody, Jennifer, Couper, David, Fedorowski, Artur,, Franceschini, Nora, Hedblad, Bo,, Hofman, Albert, Larson, Martin G, Levy, Daniel, Liu, Chunyu, Lund University., Lund University., Lund University., Lund University., Lund University., Melander, Olle,, Newton-Cheh, Christopher, Psaty, Bruce M, Raso, Francesco Mattace, Rice, Kenneth M, Rose, Kathryn M, Rotter, Jerome I, Sjögren, Marketa,, Uitterlinden, Andre, Verwoert, Germaine C, Wang, Thomas J, Witteman, Jacqueline   +27 more
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Persistent unexplained chest pain and dyspnea in a patient with coronary artery disease: a case report

BMC Cardiovascular Disorders, 2020
Background Neurogenic orthostatic hypotension, a sustained decrease in blood pressure upon standing, is caused by autonomic nervous system failure and characterized by an insufficient increase in heart rate needed to maintain blood pressure upon standing.
Sameh K. Mobarek
doaj   +1 more source

Neurogenic Orthostatic Hypotension: a Common Complication of Successful Pancreas Transplantation

Transplantation Direct, 2021
Background. Orthostatic hypotension (OH) is a poorly understood complication of simultaneous pancreas–kidney (SPK) transplantation. We sought to determine the incidence, timing, and relationship of OH to rapid glycemic control in the early posttransplant
Samantha A. Kuten, PharmD, Edward A. Graviss, PhD, Duc T. Nguyen, PhD, A. Osama Gaber, MD, Archana R. Sadhu, MD, Ericka P. Simpson, MD, Stephanie G. Yi, MD, Hemangshu Podder, MD, PhD, Anna Kagan, MD, PhD, Richard J. Knight, MD   +9 more
doaj   +1 more source