Results 101 to 110 of about 5,700,021 (349)

Label Propagation Prediction of Drug-Drug Interactions Based on Clinical Side Effects

Scientific Reports, 2015
Drug-drug interaction (DDI) is an important topic for public health and thus attracts attention from both academia and industry. Here we hypothesize that clinical side effects (SEs) provide a human phenotypic profile and can be translated into the ...
Ping Zhang, Fei Wang, Jianying Hu, R. Sorrentino   +3 more
semanticscholar   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Antimicrobial and Anti-Inflammatory Potentials of Silver Tungstate Nanoparticles, Cytotoxicity and Interference on the Activity of Antimicrobial Drugs

Drugs and Drug Candidates
Background: Bacterial resistance to antimicrobial drugs is a critical phenomenon that is hampering clinical treatments, raising the need for promising compounds that can be explored as pharmaceutical products.
Washington de Souza Leal, Juliane Zacour Marinho, Isabela Penna Ceravolo, Lucas Leão Nascimento, Antonio Otávio de Toledo Patrocínio, Marcus Vinícius Dias-Souza   +5 more
doaj   +1 more source

Clozapine treatment in patients living in the community [PDF]

, 2015
OBJECTIVE: The aim of this study was to assess clozapine treatment in the local community with respect to patient monitoring during dispensing, patient compliance through prescription refills, presence of any other existing co-morbidities and ...
Azzopardi, Lilian M., Schembri, Karl
core  

Kajian Interaksi Obat pada Pengobatan Diabetes Melitus (Dm) dengan Hipertensi di Instalasi Rawat Jalan RSUD Undata Periode Maret-juni Tahun 2014 [PDF]

, 2015
One of the chronic complications of diabetes mellitus is a disorder of macrovascular as hypertension so that in it's medicinal treatment required therapy with multiple drugs all at once that can lead to drug interactions.
Faustine, I. (Ingrid), Mukaddas, A. (Alwiyah), Nurlaelah, I. (Ida)   +2 more
core   +2 more sources

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Metabolism, Transport and Drug–Drug Interactions of Silymarin

Molecules, 2019
Silymarin, the extract of milk thistle, and its major active flavonolignan silybin, are common products widely used in the phytotherapy of liver diseases.
Ying Xie, Dingqi Zhang, Jin Zhang, Jialu Yuan   +3 more
doaj   +1 more source

Drug-drug interactions between psychiatric medications and MDMA or psilocybin: a systematic review

Psychopharmacology, 2022
Aryan Sarparast, Kelan L Thomas, B. Malcolm, Christopher S. Stauffer   +3 more
semanticscholar   +1 more source

PHARMACOGENETICS AND INTERACTIONS OF ANTIDEPRESSANTS IN THE TREATMENT OF CO-MORBID ILLNESS [PDF]

, 2009
Patients who require long-term treatment for depression have an increased risk of experiencing drug interactions since they will take medications for and/or co-morbid illness. Antidepressants can be the object of drug interactions by other substances, or
Alma Mihaljević-Peleš, Maja Živković, Marina Šagud, Nada Božina, Nikolina Jovanović   +4 more
core   +1 more source

The zinc finger domains of PARP‐1 are selectively and potently inhibited by the Au(I)‐based drugs sodium aurothiomalate and aurothioglucose

FEBS Letters, EarlyView.
PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley   +1 more source