Results 231 to 240 of about 1,993,579 (343)

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Drug-Drug Interactions and Individualized Clozapine Therapy in Patients with Depression: Insights from Real-World Data. [PDF]

Drug Des Devel Ther
Jiang L, Zhang Y, Wang J, Zhang C, Wang D.   +4 more
europepmc   +1 more source

Spotting Trends in Side Effects and Drug Interactions: Data Visualization Tools Can Supplement Decision Making for Medical Prescribers

, 2018
J. A. Dodson
openalex   +2 more sources

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Prevalence and Duration of Potential Drug-Drug Interactions Among US Nursing Home Residents, 2018-2020. [PDF]

J Am Geriatr Soc
Reich LA, Daiello LA, Berry SD, D'Amico AM, Kiel DP, Harris DA, Hayes KN, Leonard CE, Hsu YS, Zullo AR.   +9 more
europepmc   +1 more source

A physiologically-based pharmacokinetic precision dosing approach to manage dasatinib drug-drug interactions

Schwab, Matthias
openalex   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Risk prediction model for severe potential drug-drug interactions in colorectal cancer patients: a real-world data study. [PDF]

Front Pharmacol
Pei X, Yang X, Kong L.
europepmc   +1 more source

Docking aggregates and elaborate interaction of Afimetoran drug with wild and nsSNPs (R28Q, T40M, P59L, R200C), containing key residues, distances, angles and binding energies.

Obaid Habib (22615046), Saqib Ishaq (22615049), Kamran Habib (22615052), Aishma Khattak (11261634), Wei Yang (109917), Zesong Li (151039), Kainat Bukhari (22615055), Amin Ullah (12015113), Ajaz Ahmad (1408756), Qurban Ali (3700123)   +9 more
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source