Results 251 to 260 of about 1,993,579 (343)

Potential drug-drug interactions among hospitalised cardiac patients in Nepal: a prospective observational study. [PDF]

BMJ Open
Sah BK, Karna AK, Subedi S, Sah RK, Shrestha S, Dangi NB.   +5 more
europepmc   +1 more source

Risk Factors and Patterns of Drug‐Drug Interactions in Two Categories of Level‐3 Hospitals in Dhaka: A Cross‐Sectional Study [PDF]

Md Abdus Samadd, Farhan Tanvir Patwary, Md. Momin Islam, Ashfia Tasnim Munia, KM Yasif Kayes Sikdar, Md Raihan Sarkar   +5 more
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Evaluation of potentially significant drug-drug interactions among patients receiving psychotropic medications: A real-world retrospective study. [PDF]

Qatar Med J
Abu-Kuhail R, Abdallah O, Abu-Hafizah M, Alqam S, Eltorki Y, Ez Eldeen N, El Hoseny S, Al-Khuzaei N.   +7 more
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Prevalence of Cannabidiol (CBD) Use Among Patients Taking Medications with Known Drug-Drug Interactions: A Cross-Sectional Analysis. [PDF]

J Clin Med
Geneau H, Kovasala M, Brown G, Holmes S, Hime O, McNally M, McFayden M, Brewer K, Jones GK.   +8 more
europepmc   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

GNPS Feature-Based Molecular Networking as a Tool to Visualize Metabolic Toxicity from Drug-Drug Interactions: A Case Study with Methamphetamine and Ethanol. [PDF]

Anal Chem
Kim M, Kim JH, Yoo SJ, Lee S.
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Baseline medication profile and risk of CYP3A4 mediated drug-drug interactions among COVID-19 hospitalized patients in Spain. [PDF]

BMC Infect Dis
Martín-Quirós A, Soriano A, Tejerina-Picado F, Güerri-Fernández R, Cotarelo M, Molloy B, Fernández-Vigo E, Chacón F.   +7 more
europepmc   +1 more source