Results 151 to 160 of about 21,488 (194)
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In-stent Restenosis of drug-eluting Stents
Future Cardiology, 2013Drug-eluting stents (DES) have emerged as an improved alternative to bare-metal stents by demonstrating reduced rates of restenosis and target lesion revascularization. This emergence has led to the unrestricted use of DES for various indications and lesions, and subsequently revealed DES in-stent restenosis as a novel interventional therapeutic ...
Sa'ar, Minha +2 more
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Drug-Eluting Stents in the Elderly
Current Treatment Options in Cardiovascular Medicine, 2010The introduction of drug-eluting stents (DES) in 2003 has had a great impact on the management of coronary artery disease in the United States. The application of DES to older adults, the population with the highest prevalence of and worst prognosis for coronary artery disease, remains relatively more controversial.
Samip, Vasaiwala +2 more
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The American Journal of Cardiology, 2007
Drug-eluting stents (DESs) held the promise of mitigating, if not abolishing, in-stent restenosis. This led to early adoption and high penetration of DES use in percutaneous coronary intervention (PCI). Outcomes have not demonstrated an improvement in the hard end points of death and myocardial infarction with these devices, but repeat procedures for ...
Tina L Pinto, Slottow, Ron, Waksman
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Drug-eluting stents (DESs) held the promise of mitigating, if not abolishing, in-stent restenosis. This led to early adoption and high penetration of DES use in percutaneous coronary intervention (PCI). Outcomes have not demonstrated an improvement in the hard end points of death and myocardial infarction with these devices, but repeat procedures for ...
Tina L Pinto, Slottow, Ron, Waksman
openaire +2 more sources
Polymers for Drug Eluting Stents
Current Pharmaceutical Design, 2010Currently approved drug eluting stents (DES) consist of a metallic scaffold and an elutable drug dispersed in a polymer matrix that conformally surrounds the struts. These primarily biostable polymers bind the drug to the stent and modulate the elution of the drug into the arterial tissue.
Ted, Parker +2 more
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Drug-eluting stents: a critique
Heart, 2008Despite advances in the design of balloons and stents, restenosis remains a major drawback of coronary angioplasty. Multiple randomised trials have demonstrated that drug-eluting stents (DES) can significantly reduce rates of restenosis by 60–75% across both lesion and patient subsets.
N, Melikian, W, Wijns
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Current Problems in Cardiology, 2006
The introduction and widespread use of coronary stents have been the most important advancement in the percutaneous treatment of coronary artery disease since the introduction of balloon angioplasty. Coronary artery stents reduce the rate of angiographic and clinical restenosis compared to balloon angioplasty.
Amar M, Salam +2 more
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The introduction and widespread use of coronary stents have been the most important advancement in the percutaneous treatment of coronary artery disease since the introduction of balloon angioplasty. Coronary artery stents reduce the rate of angiographic and clinical restenosis compared to balloon angioplasty.
Amar M, Salam +2 more
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Mathematical Medicine and Biology, 2010
In this study, we consider a family of mathematical models to describe the elution of drug from polymer-coated stents into the arterial wall. Our models include the polymer layer, the media, the adventitia, a possible topcoat polymer layer and atherosclerotic plaque.
McGinty, Sean +3 more
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In this study, we consider a family of mathematical models to describe the elution of drug from polymer-coated stents into the arterial wall. Our models include the polymer layer, the media, the adventitia, a possible topcoat polymer layer and atherosclerotic plaque.
McGinty, Sean +3 more
openaire +4 more sources
Nature Clinical Practice Cardiovascular Medicine, 2008
Drug-eluting stents (DESs) effectively reduce angiographic restenosis and the clinical need for repeat revascularization procedures as compared with bare-metal stents. Widely publicized concerns arose recently about the incidence of late and very late stent thrombosis with the use of first-generation DESs.
Windecker S, Jüni P
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Drug-eluting stents (DESs) effectively reduce angiographic restenosis and the clinical need for repeat revascularization procedures as compared with bare-metal stents. Widely publicized concerns arose recently about the incidence of late and very late stent thrombosis with the use of first-generation DESs.
Windecker S, Jüni P
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Drug Eluting Stents and Beyond
Current Pharmaceutical Design, 2008The present review discusses the mechanism of late stent thrombosis and its distinction from restenosis and summarizes the advisory note issued by FDA on the proper usage of different treatments available for atherosclerosis. In light of the latest developments, a plethora of new stents have been and continue to be developed globally. Hence, there is a
Ashish, Rastogi, Salomon, Stavchansky
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Dimensions of Critical Care Nursing, 2007
Coronary artery disease is the number 1 killer of Americans. There are many efforts underway to prevent and treat this life-threatening disease. One such treatment is the placement of drug-eluting stents. However, recent reports that show an increased risk of potentially life-threatening complications associated with drug-eluting stents have surfaced ...
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Coronary artery disease is the number 1 killer of Americans. There are many efforts underway to prevent and treat this life-threatening disease. One such treatment is the placement of drug-eluting stents. However, recent reports that show an increased risk of potentially life-threatening complications associated with drug-eluting stents have surfaced ...
openaire +2 more sources