Results 1 to 10 of about 1,693,725 (358)

Systemic Lupus Erythematosus in a Patient with Ulcerative Colitis: Co-Existing or Drug-Induced?

Journal of Clinical Rheumatology and Immunology, 2019
We report a 49-year-old lady with ulcerative colitis (UC) who subsequently developed systemic lupus erythematosus (SLE) ten years later. By reviewing the drug history and serum autoimmune panel, we hypothesize that systemic lupus erythematosus may occur ...
Frances Feisi Sun, Nga Lai Chan, Tsz Ching Chan, Ka Long Leung, Yuk Wo Aaron Siu, Chi Hang Sui, Chak Lam Yu, Ho Yin Chung   +7 more
doaj   +2 more sources

Drug-Induced Phototoxicity in Vitiligo: The Role of Hydrochlorothiazide in Photosensitivity Dermatitis. [PDF]

Case Rep Dermatol Med
Parga AD, Dubin C, Rudikoff D.
europepmc   +3 more sources

Caenorhabditis elegans as a model system for studying drug induced mitochondrial toxicity [PDF]

, 2015
Today HIV-1 infection is recognized as a chronic disease with obligatory lifelong treatment to keep viral titers below detectable levels. The continuous intake of antiretroviral drugs however, leads to severe and even life-threatening side effects ...
Brul, Stanley, de Boer, Richard, De Vos, Winnok, Manders, Erik MM, Smith, Ruben L, van der Spek, Hans   +5 more
core   +14 more sources

Comparative Metabolomic Profiling of the Metabolic Differences of Δ9-Tetrahydrocannabinol and Cannabidiol

Molecules, 2022
More than one hundred cannabinoids have been found in cannabis. Δ9-Tetrahydrocannabinol (THC) is the recognized addictive constituent in cannabis; however, the mechanisms underlying THC-induced toxicity remain elusive.
Qianru Rao, Ting Zhang, Manyun Dai, Bin Li, Qianlun Pu, Min Zhao, Yan Cheng, Dongmei Yan, Qi Zhao, Zhanxuan E. Wu, Fei Li   +10 more
doaj   +1 more source

Metabolic Profile of C-Prenyl Coumarins Using Mass Spectrometry-Based Metabolomics

Molecules, 2021
C-prenyl coumarins (C-PYCs) are compounds with similar structures and various bioactivities, which are widely distributed in medicinal plants. Until now, the metabolic characterizations of C-PYCs and the relationship between metabolism and bioactivities ...
Yan Cheng, Xiaofang Ma, Qi Zhao, Chunyan Wang, Dongmei Yan, Fei Li   +5 more
doaj   +1 more source

Parabacteroides distasonis ameliorates hepatic fibrosis potentially via modulating intestinal bile acid metabolism and hepatocyte pyroptosis in male mice

Nature Communications, 2023
Parabacteroides distasonis (P. distasonis), part of the gut microbiome, was reported to play a role in diabetes, colorectal cancer and inflammatory bowel disease. Here the authors report that P.
Qi Zhao, Man-Yun Dai, Ruo-Yue Huang, Jing-Yi Duan, Ting Zhang, Wei-Min Bao, Jing-Yi Zhang, Shao-Qiang Gui, Shu-Min Xia, Cong-Ting Dai, Ying-Mei Tang, Frank J. Gonzalez, Fei Li   +12 more
doaj   +1 more source

Efficacy of low-dose pramipexole augmentation in the treatment of refractory psychotic depression complicated with tardive dyskinesia: a case report

Psychiatry and Clinical Psychopharmacology, 2021
Tardive dyskinesia (TD) is a severe complication of antipsychotic treatment. Pramipexole can be effective in the treatment of TD due to its D3 dopamine receptor agonist effect.
Arzu Erkan, Sebnem Pirildar, Ahmet Acarer, Fisun Akdeniz   +3 more
doaj   +1 more source

Association of PNPLA3 rs738409 G/C gene polymorphism with nonalcoholic fatty liver disease in children: a meta-analysis

BMC Medical Genetics, 2020
Background Nonalcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease worldwide. Current studies have shown that PNPLA3 (Patatin-like phospholipase domain containing 3) rs738409 G/C gene polymorphism is associated ...
Shan Tang, Jing Zhang, Ting Ting Mei, Hai Qing Guo, Xin Huan Wei, Wen Yan Zhang, Ya Li Liu, Shan Liang, Zuo Peng Fan, Li Xia Ma, Wei Lin, Yi Rong Liu, Li Xia Qiu, Hai Bin Yu   +13 more
doaj   +1 more source

Drug-induced pigmentation

Pigment International, 2022
Around 10% to 20% of all cases of acquired hyperpigmentation are drug-induced. The underlying pathogenesis for drug-induced pigmentation includes melanin accumulation, drug accumulation, toxic effects on melanocytes, and hypersecretion of ...
Arunachalam Narayanan, Laxmisha Chandrashekhar   +1 more
doaj   +1 more source

Clinical Outcome and Risk Assessment in Hospitalized COVID-19 Patients with Elevated Transaminases and Acute Kidney Injury: A Single Center Study

Oman Medical Journal, 2022
Objectives: Initial reports indicate a high incidence of abnormal aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels in patients with COVID-19 and possible association with acute kidney injury (AKI).
Yulia Khruleva, Zhanna Kobalava, Olga Arisheva, Marina Efremovtseva, Irina Garmash, Maria Vatsik-Gorodetskaya, Mohammed Al Jarallah, Peter A Brady, Ibrahim Al-Zakwani, Rajesh Rajan   +9 more
doaj   +1 more source