Results 341 to 350 of about 10,944,767 (389)
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Current Gastroenterology Reports, 2007
Many drugs have been known to cause diarrhea, although their mechanism of action has not been well described. The gastrointestinal tract may become dysregulated when exposed to a drug that could disrupt mechanisms controlling mucosal permeability, transport, motility, and gut metabolism. This review examines the mechanism by which drugs induce diarrhea
Bincy Abraham, Joseph H. Sellin
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Many drugs have been known to cause diarrhea, although their mechanism of action has not been well described. The gastrointestinal tract may become dysregulated when exposed to a drug that could disrupt mechanisms controlling mucosal permeability, transport, motility, and gut metabolism. This review examines the mechanism by which drugs induce diarrhea
Bincy Abraham, Joseph H. Sellin
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Veterinary Clinics of North America: Small Animal Practice, 1999
The prevalence of uroliths that contain drugs, their metabolites, or toxic ingredients in dogs, cats, and other animals is unknown. The authors examine specific drugs and their use in the animal population. They discuss these drugs in terms of uroliths and urolith formation in a variety of animals, making recommendations on which drugs can be safely ...
C A, Osborne +9 more
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The prevalence of uroliths that contain drugs, their metabolites, or toxic ingredients in dogs, cats, and other animals is unknown. The authors examine specific drugs and their use in the animal population. They discuss these drugs in terms of uroliths and urolith formation in a variety of animals, making recommendations on which drugs can be safely ...
C A, Osborne +9 more
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Drug-Induced Liver Injury - Types and Phenotypes.
New England Journal of Medicine, 2019Drug-Induced Liver Injury The liver has a range of responses to drug-induced injury, with a number of phenotypes.
J. Hoofnagle, E. Björnsson
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Clinics in Dermatology, 2014
A variety of drugs may provoke acne, with drug-induced acne (DIA) often having some specific clinical and histopathologic features. DIA is characterized by a medical history of drug intake, sudden onset, and an unusual age of onset, with a monomorphous eruption of inflammatory papules or papulopustules.
Jana Kazandjieva, Nikolai Tsankov
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A variety of drugs may provoke acne, with drug-induced acne (DIA) often having some specific clinical and histopathologic features. DIA is characterized by a medical history of drug intake, sudden onset, and an unusual age of onset, with a monomorphous eruption of inflammatory papules or papulopustules.
Jana Kazandjieva, Nikolai Tsankov
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Dermatologic Clinics, 2014
Drug-induced photosensitivity is common. The principal mechanism of systemic drug photosensitivity is phototoxicity and the principal mechanism of topical drug photosensitivity is photoallergy. Photopatch testing is helpful to determine suspected topical agent photoallergies (eg, from ultraviolet filters in sunscreens) but generally not helpful in ...
Dawe, Robert S., Ibbotson, Sally H.
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Drug-induced photosensitivity is common. The principal mechanism of systemic drug photosensitivity is phototoxicity and the principal mechanism of topical drug photosensitivity is photoallergy. Photopatch testing is helpful to determine suspected topical agent photoallergies (eg, from ultraviolet filters in sunscreens) but generally not helpful in ...
Dawe, Robert S., Ibbotson, Sally H.
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Expert Opinion on Drug Safety, 2003
Drugs may cause several overlapping syndromes of cholestasis, the pathophysiological syndrome resulting from impaired bile flow. These reactions comprise approximately 17% of all hepatic adverse drug reactions (ADRs) and they may be severe. Causes of 'pure' (bland) cholestasis include oestrogens and anabolic steroids; rarer associations are with ...
Lakshumanan S Velayudham +1 more
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Drugs may cause several overlapping syndromes of cholestasis, the pathophysiological syndrome resulting from impaired bile flow. These reactions comprise approximately 17% of all hepatic adverse drug reactions (ADRs) and they may be severe. Causes of 'pure' (bland) cholestasis include oestrogens and anabolic steroids; rarer associations are with ...
Lakshumanan S Velayudham +1 more
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Toxicology, 2005
Drug-induced lupus (DIL) refers to an idiosyncratic side effect of numerous, apparently unrelated, medications, in which symptoms overlap with those of systemic lupus erythematosus. DIL is reversible by discontinuation of the medication. The etiological mechanism underlying DIL is linked to the inherent susceptibility of the adaptive immune system to ...
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Drug-induced lupus (DIL) refers to an idiosyncratic side effect of numerous, apparently unrelated, medications, in which symptoms overlap with those of systemic lupus erythematosus. DIL is reversible by discontinuation of the medication. The etiological mechanism underlying DIL is linked to the inherent susceptibility of the adaptive immune system to ...
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Expert Opinion on Drug Safety, 2003
Therapeutic agents from virtually every pharmacological class have been implicated in the development of drug-induced vasculitis. Clinical manifestations range from small vessel hypersensitivity vasculitis and leukocytoclastic vasculitis to clinical syndromes indistinguishable from classical systemic forms of vasculitis such as Wegener's granulomatosis,
Mittie K Doyle, Marta Lucia Cuellar
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Therapeutic agents from virtually every pharmacological class have been implicated in the development of drug-induced vasculitis. Clinical manifestations range from small vessel hypersensitivity vasculitis and leukocytoclastic vasculitis to clinical syndromes indistinguishable from classical systemic forms of vasculitis such as Wegener's granulomatosis,
Mittie K Doyle, Marta Lucia Cuellar
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Drug-Induced Hepatotoxicity or Drug-Induced Liver Injury
Clinics in Liver Disease, 2009Drug-induced hepatotoxicity is underreported and underestimated in the United States. It is an important cause of acute liver failure. Common classes of drugs causing drug-induced hepatotoxicity include antibiotics, lipid lowering agents, oral hypoglycemics, psychotropics, antiretrovirals, acetaminophen, and complementary and alternative medications ...
Ashutosh Barve +4 more
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American Journal of Clinical Pathology, 1974
Drug-induced bleeding disorders can be categorized according to the manner in which they embarrass hemostasis. Thus, there are drugs which: (1) are themselves anticoagulants, (2) potentiate the action of simultaneously administered anticoagulants, (3) when discontinued induce bleeding diatheses among patients who continue to receive anticoagulants, (4)
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Drug-induced bleeding disorders can be categorized according to the manner in which they embarrass hemostasis. Thus, there are drugs which: (1) are themselves anticoagulants, (2) potentiate the action of simultaneously administered anticoagulants, (3) when discontinued induce bleeding diatheses among patients who continue to receive anticoagulants, (4)
openaire +4 more sources