Results 31 to 40 of about 10,944,767 (389)
Genetic and Molecular Factors in Drug-Induced Liver Injury: A Review [PDF]
, 2007 The diagnosis of drug-induced liver injury (DILI) is challenging and based on complex diagnostic criteria. DILI falls into two main categories i) intrinsic 'dose-dependent' Type A reactions ii) 'idiosyncratic' or Type B reactions (which are usually not ...
Andrade, RJ +6 more
core +3 more sources
FEBS Letters, 2006 Drug‐induced phospholipidosis is characterized by intracellular accumulation of phospholipids with lamellar bodies, most likely from an impaired phospholipid metabolism of the lysosome. Organs affected by phospholipidosis exhibit inflammatory reactions and histopathological changes.
Nora Anderson, Jürgen Borlak
openaire +3 more sources
Severe drug-induced liver injury associated with prolonged use of Linezolid [PDF]
, 2010 This study aims to describe a patient developing concomitant severe liver failure and lactic acidosis after long-term treatment with linezolid. A 55-year-old Caucasian woman developed concomitant severe liver failure and lactic acidosis after a treatment
Benoit, Dominique +7 more
core +1 more source
Corneal arcus and xanthomas in homozygous familial hypercholesterolemia: First report from China
Indian Journal of Ophthalmology, 2013 We report the case of a 12-year-old male who developed corneal arcus and multiple skin lesions with a 10-year history of xanthomas. The lesions appeared over his fingers, hands, elbows, knees, buttocks and feet.
Xin Meng +5 more
doaj +1 more source
A Missense Variant in PTPN22 is a Risk Factor for Drug-induced Liver Injury [PDF]
, 2019 BACKGROUND & AIMS: We performed genetic analyses of a multiethnic cohort of patients with idiosyncratic drug-induced liver injury (DILI) to identify variants associated with susceptibility.
Cirulli, Elizabeth T. +4 more
core +1 more source
Caenorhabditis elegans as a model system for studying drug induced mitochondrial toxicity [PDF]
, 2015 Today HIV-1 infection is recognized as a chronic disease with obligatory lifelong treatment to keep viral titers below detectable levels. The continuous intake of antiretroviral drugs however, leads to severe and even life-threatening side effects ...
Brul, Stanley +5 more
core +8 more sources
Trimetazidine-Induced Parkinsonism: A Systematic Review
Frontiers in Neurology, 2020 Importance: Trimetazidine (TMZ) is a medication given to patients with stable coronary artery disease. While it is reportedly well-tolerated, there are increasing numbers of reports of adverse events such as parkinsonism.Objectives: The purpose of this ...
Anna Marielle B. Dy +5 more
doaj +1 more source
Pityriasis rubra pilaris-like eruption following insulin therapy initiation
Dermatology Practical & Conceptual, 2016 Pityriasis rubra pilaris (PRP) is a chronic disorder of keratinization of unclear pathogenesis. PRP-like eruptions induced by drugs have rarely been described.
Talel Badri +5 more
doaj +1 more source
Drug-Induced Steatohepatitis [PDF]
Clinics in Liver Disease, 2013 Nonalcoholic fatty liver disease (NAFLD) is currently the most common cause of chronic liver disease in the United States. The term NALFD was first used by Ludwig in 1980 to describe the presence of hepatic steatosis and steatohepatitis in a series of patients with no identifiable cause.
Vaishali Patel, Arun J. Sanyal
openaire +3 more sources
Systemic Lupus Erythematosus in a Patient with Ulcerative Colitis: Co-Existing or Drug-Induced?
Journal of Clinical Rheumatology and Immunology, 2019 We report a 49-year-old lady with ulcerative colitis (UC) who subsequently developed systemic lupus erythematosus (SLE) ten years later. By reviewing the drug history and serum autoimmune panel, we hypothesize that systemic lupus erythematosus may occur ...
Frances Feisi Sun +7 more
doaj +1 more source