Results 81 to 90 of about 6,563,401 (267)
Fixed drug eruption induced by atenolol
H Belhadjali, O Trimech, M Youssef, I Elhani, J ZiliDepartment of Dermatology, Fattouma Bourguiba Hospital, Monastir, Tunisia Abstract: Fixed drug eruption (FDE) is characterized by recurrent well-defined lesions in the same location each time ...
H Belhadjali +4 more
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Brief strategic family therapy for adolescent drug abuse. [PDF]
To ensure that treatment providers apply the most current scientifically supported approaches to their patients, NIDA has supported the development of the "Therapy Manuals for Drug Addiction" series.
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Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Drug consumption rooms in Europe: Organisational overview. [PDF]
This report provides an overview of the organisation and working methods of drug consumption rooms (DCRs) in Europe. It offers information about the functioning of DCRs as well as on the organisation and structure of such facilities and aims to benefit ...
Woods, Sara
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Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Steroid induced mania in an elderly patient
In the present context, steroids are important therapeutic agents used in the management of various diseases. Existing literature suggests that various steroids are associated with psychiatric manifestations such as psychosis, depression, mania, dementia/
Sandeep Grover +3 more
doaj +1 more source
Response to Comments, Second Draft: Kansas Induced Seismicity Action Plan [2014]
September 24, 2014"The Kansas Task Force on Induced Seismicity recently closed an open comment period in response to its second draft State Action Plan (SAP).
Kansas Induced Seismicity State Task Force.
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source

