Results 1 to 10 of about 110,228 (118)
Successful outcomes of pediatric dacryocystorhinostomy with adjunctive 5-fluorouracil [PDF]
Frontiers in OphthalmologyPurposeTo determine whether nasal intramucosal 5-fluorouracil (5-FU) injection improves outcomes after external dacryocystorhinostomy (DCR) in pediatric patients with nasolacrimal duct obstruction (NLDO).MethodsMulti-center retrospective non-comparative ...
Alina K. Sinha +9 more
doaj +2 more sources
5-Fluorouracil (5-FU) Cardiotoxicity: A Stressful Event [PDF]
Case Reports in Cardiology5-Fluorouracil (5-FU), a chemotherapeutic agent, is routinely used for solid tumors. Known cardiotoxic effects of 5-FU include fatal arrhythmias, myocardial infarctions, and coronary vasospasms.
Yash Desai +5 more
doaj +2 more sources
Research in Pharmaceutical Sciences, 2022 Background and purpose: Several pharmaceutical formulations were investigated to improve the solubility of 5-fluorouracil to enhance bioavailability and therapeutic efficacy. This study aimed to examine the potential use of cyclodextrin-based nanosponges
Hadeia Mashaqbeh +4 more
doaj +1 more source
Journal of Dermatology and Dermatologic Surgery, 2021 Background: Vitiligo is a dermatological challenge with a major socio-psychological concern. Despite the availability of numerous medical and surgical treatment options, a single universally reliable therapeutic modality is yet to emerge due to the ...
Ankit K Singrodia +5 more
doaj +1 more source
Histopathological Effects of 5-Fluorouracil on the Liver of Male Rabbits ( with and without Folic Acid administration ) [PDF]
Al-Rafidain Dental Journal, 2016 Aims : The objective of this study is to evaluate the effects of 5-fluorouracil (5-FU) on the liver tissue of rabbits, as well as the effect of folic acid on the effectiveness of 5-FU on the rabbit's liver. Materials and Methods: In this study nine adult
Makarem Hameed Ahmad
doaj +1 more source
The Effect of the Combinations of 5-Fluorouracil, Leptin and Leptin Antagonist in Glioblastoma
Proceedings, 2019 Glioblastoma (GB) is the most aggressive form of brain tumor and resistant to chemotherapy. New therapeutic approaches are needed to improve the efficacy of chemotherapy. It was reported that there may be a relationship between obesity and poor prognosis
Filiz Taşpinar +2 more
doaj +1 more source
Clinical and Translational Medicine, 2022 Background To date, 5‐fluorouracil‐based chemotherapy is very important for locally advanced or metastatic colorectal cancer (CRC). However, chemotherapy resistance results in tumor recurrence and metastasis, which is a major obstacle for treatment of ...
Lanqing Wang +11 more
doaj +1 more source
Effectiveness of 5-Fluorouracil 5% Cream in Perianal Condylomata Accuminata Treatment: A Case Report
Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology), 2021 Background: Condylomata accuminata is a sexually transmitted disease, appeared as verrucous or cauliflower-like papules or warts in the anogenital. It is caused by human papillomavirus (HPV), mostly type 6 and 11.
Dea Florensia, Lita Setyowatie
doaj +1 more source
Quercetin synergistically potentiates the anti-metastatic effect of 5-fluorouracil on the MDA-MB-231 breast cancer cell line [PDF]
Iranian Journal of Basic Medical Sciences, 2021 Objective(s): Breast cancer (BC) cells’ ability to metastasize to other tissues increases mortality. The Matrix metalloproteinases 2 and 9 (MMP-2 and MMP-9) facilitate cancer cell migration.
Mohammadreza Roshanazadeh +2 more
doaj +1 more source
Evaluation of Efficacy and Safety Topical 5-Fluorouracil 0.5% in Treatment of Resistant Vitiligo [Alone or After Microneedling]; A pilot Study [PDF]
International Journal of Medical Arts, 2021 Background: Vitiligo is a chronic acquired disorder characterized by the depigmented macules. There are many treatment options, but the response is variable and unsatisfactory.
Sara Galal, Moshiraly Ali, Fatma Elzeiny
doaj +1 more source