Results 1 to 10 of about 106,229 (120)

HCT116 ve HT29 Kolon Kanseri Hücrelerinde 5-Florourasil Kaynaklı Hücre Ölümünün Fourier Dönüşümlü Kızılötesi Spektroskopisi ile İncelenmesi

open access: yesDüzce Üniversitesi Bilim ve Teknoloji Dergisi, 2023
Kolon kanseri, tüm dünyada yaygın olan ve yüksek oranda ölümcül bir kanser tipidir. Tüm kanserlerde olduğu gibi kolon kanserinin seyrinin izlenmesi kritik bir öneme sahiptir.
Ferdane Danışman Kalındemirtaş   +2 more
doaj   +1 more source

Weak complexation of 5-fluorouracil with β-cyclodextrin, carbonate, and dianhydride crosslinked β-cyclodextrin: in vitro and in silico studies

open access: yesResearch in Pharmaceutical Sciences, 2022
Background and purpose: Several pharmaceutical formulations were investigated to improve the solubility of 5-fluorouracil to enhance bioavailability and therapeutic efficacy. This study aimed to examine the potential use of cyclodextrin-based nanosponges
Hadeia Mashaqbeh   +4 more
doaj   +1 more source

Microneedling with topical 5-fluorouracil in the localized stable vitiligo – Is this the way out? – Our experience: A hospital-based study

open access: yesJournal of Dermatology and Dermatologic Surgery, 2021
Background: Vitiligo is a dermatological challenge with a major socio-psychological concern. Despite the availability of numerous medical and surgical treatment options, a single universally reliable therapeutic modality is yet to emerge due to the ...
Ankit K Singrodia   +5 more
doaj   +1 more source

Histopathological Effects of 5-Fluorouracil on the Liver of Male Rabbits ( with and without Folic Acid administration ) [PDF]

open access: yesAl-Rafidain Dental Journal, 2016
Aims : The objective of this study is to evaluate the effects of 5-fluorouracil (5-FU) on the liver tissue of rabbits, as well as the effect of folic acid on the effectiveness of 5-FU on the rabbit's liver. Materials and Methods: In this study nine adult
Makarem Hameed Ahmad
doaj   +1 more source

Quercetin synergistically potentiates the anti-metastatic effect of 5-fluorouracil on the MDA-MB-231 breast cancer cell line [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2021
Objective(s): Breast cancer (BC) cells’ ability to metastasize to other tissues increases mortality. The Matrix metalloproteinases 2 and 9 (MMP-2 and MMP-9) facilitate cancer cell migration.
Mohammadreza Roshanazadeh   +2 more
doaj   +1 more source

Targeting DCLK1 overcomes 5‐fluorouracil resistance in colorectal cancer through inhibiting CCAR1/β‐catenin pathway‐mediated cancer stemness

open access: yesClinical and Translational Medicine, 2022
Background To date, 5‐fluorouracil‐based chemotherapy is very important for locally advanced or metastatic colorectal cancer (CRC). However, chemotherapy resistance results in tumor recurrence and metastasis, which is a major obstacle for treatment of ...
Lanqing Wang   +11 more
doaj   +1 more source

Effectiveness of 5-Fluorouracil 5% Cream in Perianal Condylomata Accuminata Treatment: A Case Report

open access: yesBerkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology), 2021
Background: Condylomata accuminata is a sexually transmitted disease, appeared as verrucous or cauliflower-like papules or warts in the anogenital. It is caused by human papillomavirus (HPV), mostly type 6 and 11.
Dea Florensia, Lita Setyowatie
doaj   +1 more source

Evaluation of Efficacy and Safety Topical 5-Fluorouracil 0.5% in Treatment of Resistant Vitiligo [Alone or After Microneedling]; A pilot Study [PDF]

open access: yesInternational Journal of Medical Arts, 2021
Background: Vitiligo is a chronic acquired disorder characterized by the depigmented macules. There are many treatment options, but the response is variable and unsatisfactory.
Sara Galal, Moshiraly Ali, Fatma Elzeiny
doaj   +1 more source

The Effect of the Combinations of 5-Fluorouracil, Leptin and Leptin Antagonist in Glioblastoma

open access: yesProceedings, 2019
Glioblastoma (GB) is the most aggressive form of brain tumor and resistant to chemotherapy. New therapeutic approaches are needed to improve the efficacy of chemotherapy. It was reported that there may be a relationship between obesity and poor prognosis
Filiz Taşpinar   +2 more
doaj   +1 more source

Evolution of Adjuvant Chemotherapy and Efficacy of Commonly Used Regimens in Colorectal Cancer [PDF]

open access: yesAl Ameen Journal of Medical Sciences, 2012
Objective: to know the evolution of adjuvant chemotherapy treatment given and to evaluate the efficacy of two commonly used regimens. Background: Colorectal cancer in Indian population is on upward swing due to the change in dietary habits and many other
S.M. Adiga   +5 more
doaj  

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