Results 41 to 50 of about 11,853,684 (309)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Comparison of Efficacy of Intralesional Triamcinolone and Combination of Triamcinolone With 5-Fluorouracil in The Treatment of Keloid

Pakistan Armed Forces Medical Journal
Objectives: To study the efficacy of intralesional Triamcinolone and combination of Triamcinolone with 5-Fluorouracil in the treatment of keloid in terms or reduction in height of lesion. Study Design: Cross-sectional analytical study.
Shah Faisal, Shahid Hameed, Abdul Majid, Afia Ayub, Siyab Ahmad, Muhammad Ali Nasir   +5 more
doaj   +1 more source

Ameliorative effect of vitamin C against 5-fuorouracil-induced hepatotoxicity in mice: A light and electron microscope study

Journal of Basic and Applied Zoology, 2014
5-Fluorouracil is one of the most widely used chemotherapeutic agents in case of hepatic neoplasms. The object of this study was to determine the effectiveness of vitamin C in alleviating 5-fluorouracil-induced hepatotoxicity in male mice.
Nadia R.A. Abou-Zeid
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Synthesis and in vitro anticancer properties of a novel neodymium(III) complex containing tungstogermanate and 5-fluorouracil

, 2018
A novel neodymium(III) complex containing tungstogermanate and 5-fluorouracil, K11(C4H4FN2O2)2Nd(GeW11O39)2·15H2O (FNdGeW), was synthesized and its structure was characterized by 1H NMR, IR, XRD, and TG-DSC.
Qingyin Wu (4783203), Zengqiang Li (725869), Haibin Liu (403499), Ce Zhao (5183348), Danfeng Zhang (1643638), Baoyang Zhou (5183345)   +5 more
core   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Curcuma longa extract protects against 5-fluorouracil-induced oral mucositis in hamsters

, 2022
Curcumin, contained at Turmeric (Curcumalonga), can exert many beneficial pleiotropic activities in the gastrointestinal tract. This study evaluated the antioxidant and anti-inflammatory activity of C.
Luiz Alberto Lira Soares (3607856), Maria Luiza Diniz de Sousa Lopes (14073330), Edna Maria Silva (14073315), Amanda Lanna Andrade Barbalho (14073321), Iolanda Augusta Fernandes de Matos (14073324), Janaina Carla Barbosa Machado (14073336), Matheus Araujo dos Santos (14073327), Caroline Addison Carvalho Xavier de Medeiros (14073333), Aurigena Antunes de Araújo (14073312), Cristiane Assunção da Costa Cunha Mafra (14073318), Raimundo Fernandes de Araújo (14073339), Magda Rhayanny Assunção Ferreira (7492277), Rubens Maribondo do Nascimento (5528156), Íris do Céu Clara Costa (10399338), Gerlane Coelho Bernardo Guerra (5379341)   +14 more
core   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

5-fluorouracil metabolism.

, 2016
5-fluorouracil metabolism.
Bruna Cerbelli (3133278), Marina Borro (440234), Claudia Sebastiani (3133269), Maurizio Simmaco (440241), Federica Mazzuca (3133257), Luca Marchetti (3133275), Andrea Botticelli (3133263), Giovanna Gentile (3133266), Paolo Marchetti (393307), Adriana Romiti (3133281), Luana Lionetto (3133254), Concetta Elisa Onesti (3133272), Mario Occhipinti (3133260), Lidia Strigari (51527)   +13 more
core   +1 more source

Supramolecular Tripeptide Hydrogel Assembly with 5-Fluorouracil [PDF]

, 2019
In this work, we present Thioflavin T fluorescence, transmission electron microscopy (TEM), circular dichroism (CD), Fourier-transformed infrared (FT-IR), and oscillatory rheometry studies applied to an antineoplastic drug, 5-fluorouracil (5-FU ...
Ana M. Garcia, Domenico Marson, Evelina Parisi, Ana M. Garcia, Paola Posocco, Silvia Marchesan   +5 more
core   +1 more source