Results 51 to 60 of about 175,639 (315)

Advanced head and neck cancer: Long-term results of chemo-radiotherapy, complications and induction of second malignancies [PDF]

, 2001
Background: Chemo-radiotherapy is superior to radiotherapy alone in the treatment of advanced, inoperable head and neck cancer. The long-term treatment results, the induction of second malignant tumors, and other long-term toxicities are not well defined.
Aydemir, Ü., Hartenstein, R., Munker, Reinhold, Pohlmann, H., Purmale, L., Reitmeier, M., Schorer, H.   +6 more
core   +1 more source

Dual Acidic pH‐Responsive Post‐Crosslinked E‐Spun Nanofibrous Scaffolds Exhibiting Enhanced Disassembly and Release for Localized Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Dual acidic pH‐responsive degradable e‐spun nanofibrous mats crosslinked with acid‐labile imine and boronic ester linkages that exhibit rapid degradation and enhanced release of encapsulated anticancer drugs through their acid‐catalyzed hydrolysis and their doxorubicin‐loaded mats having desired antitumoral activity and hemocompatibility, as promising ...
Sofia Nieves Casillas‐Popova, Arianna Cirillo, Cameron D. Skinner, Dajana Vuckovic, Jung Kwon Oh   +4 more
wiley   +1 more source

Toca 511 gene transfer and treatment with the prodrug, 5-fluorocytosine, promotes durable antitumor immunity in a mouse glioma model. [PDF]

, 2017
BackgroundToca 511 (vocimagene amiretrorepvec) is a retroviral replicating vector encoding an optimized yeast cytosine deaminase (CD). Tumor-selective expression of CD converts the prodrug, 5-fluorocytosine (5-FC), into the active chemotherapeutic, 5 ...
Gruber, Harry E, Hiraoka, Kei, Inagaki, Akihito, Jolly, Douglas J, Kasahara, Noriyuki, Kato, Yuki, Lopez Espinoza, Fernando, Mendoza, Daniel, Mitchell, Leah A, Robbins, Joan M   +9 more
core   +1 more source

Exploring the Potential of Zero‐Dimensional Carbon Nanomaterials in Photoluminescent, Electrochemiluminescent and Electrochemical Sensors

Advanced Materials Interfaces, EarlyView.
Zero‐dimensional carbon nanomaterials are presented as multifunctional platforms linking structure, property, and sensing performance. Surface engineering and heteroatom doping modulate electron‐transfer and luminescent behavior, enabling electrochemical, photoluminescent, and electrochemiluminescent detection. Fundamental design principles, analytical
Gustavo Martins, Jeferson Luiz Gogola, Ava Gevaerd, Cristiane Kalinke, Paulo Roberto de Oliveira, Fabio Roberto Caetano, Bruno Campos Janegitz, Márcio Fernando Bergamini, Luiz Humberto Marcolino‐Junior   +8 more
wiley   +1 more source

Chemotherapy related encephalopathy in a patient with Stage IV cervical carcinoma treated with cisplatin and 5-fluorouracil: a case report [PDF]

, 2009
INTRODUCTION: Chemotherapy related encephalopathy is commonly reported with certain forms of chemotherapy but few reports note an association with low dose 5-Fluorouracil.
Chue, AL, Fernando, Indy, Hussain, Syed, Yates, David   +3 more
core   +3 more sources

Nanozymes at the Bio‐Nano Interface: From Synthesis, Defect Engineering, Catalytic Behavior in Biological Microenvironments, and Biosafety Implications

Advanced Materials Interfaces, EarlyView.
Nanozymes (NZs) have emerged as versatile artificial enzymes with tunable catalytic properties driven by atomic coordination, defect engineering, and surface chemistry. This review presents a bio–nano interface framework linking synthesis strategies, structural design, and catalytic behavior within complex biological microenvironments.
Karen Guadalupe Quintero‐Garrido, Aída Jimena Velarde‐Salcedo, Alejandro López‐Amador, Noé Arjona, Citlali Uitz Toalá, Carmen Gonzalez, Beatriz Liliana España‐Sánchez   +6 more
wiley   +1 more source

Grape seed extract dose-responsively decreases disease severity in a rat model of mucositis; concomitantly enhancing chemotherapeutic effectiveness in colon cancer cells.

PLoS ONE, 2014
ObjectiveMucositis is a serious disorder of the gastrointestinal tract that results from cancer chemotherapy. We investigated the effects of increasing grape seed extract doses on the severity of chemotherapy in a rat model and its coincident impact on ...
Ker Yeaw Cheah, Gordon Stanley Howarth, Susan Elaine Putnam Bastian   +2 more
doaj   +1 more source

Histopathological Study of 5−Fluorouracil with and without Folic Acid administration on The Gastric Mucosa of Male Rabbits [PDF]

Al-Rafidain Dental Journal, 2017
Aims : To study the effects of 5−Fluorouracil (5−FU) on the gastric mucosa of rabbits and to evaluate the effect of folic acid (FA) on these effectiveness.
Alhan Daham Hadi Al –Moula
doaj   +1 more source

Inhibition of growth of colorectal cancer patient-derived subcutaneous xenografts using combined Wnt signaling pathway inhibitor and 5‑fluorouracil

Исследования и практика в медицине, 2022
Purpose of the study. Was to analyze antitumor efficacy of the XAV 939 Wnt signaling pathway inhibitor and its combination with 5 fluorouracil in subcutaneous xenografts derived from patients with colorectal cancer.Materials and methods.
A. S. Goncharova, A. V. Galina, D. V. Khodakova, G. Yu. Egorov, A. Yu. Maksimov, E. N. Kolesnikov, E. F. Komarova, A. A. Kiblitskaya, E. V. Zaikina, L. Z. Kurbanova, M. V. Mindar   +10 more
doaj   +1 more source

Single-strand selective monofunctional uracil-DNA glycosylase (SMUG1) deficiency is linked to aggressive breast cancer and predicts response to adjuvant therapy [PDF]

, 2013
Uracil in DNA is an important cause of mutagenesis. SMUG1 is a uracil DNA glycosylase that removes uracil through base excision repair. SMUG1 also processes radiation induced oxidative base damage as well as 5-fluorouracil incorporated into DNA during
Abdel-Fatah, TMA, Agarwal, D, Albarakati, N, Ball, G, Bowell, L, Chan, S, Ellis, IO, Hawkes, C, Madhusudan, S, Moseley, P   +9 more
core   +1 more source